Applications for Meprin alpha Subunit/MEP1A Antibody (364312) [PerCP] Application Recommended Usage CyTOF-ready Optimal dilutions of this antibody should be experimentally determined. Immunoprecipitation Optimal dilutions of this antibody should be experimentally determined. Intracellular Staining by...
RayBio® Human Meprin alpha ELISA Kit for Serum, Plasma, and Cell Culture Supernatants. CODE:ELH-MEP1A-1 Number of Plates: Antigen Information Accession Number: Q16819 Gene ID: 4224 Protein Name & Synonyms: Meprin A subunit alpha (EC 3.4.24.18) (Endopeptidase-2) (N-benzoyl-L-tyrosyl-...
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Meprin A Alpha (Mep1A) Polyclonal Antibody 详情介绍: Target Name Meprin A Alpha (MEP1a) Target Synonyms PPHA; PABA Peptide Hydrolase; Endopeptidase-2; N-benzoyl-L-tyrosyl-P-amino-Benzoic Acid Hydrolase Subunit Alpha; PABA Peptide Hydrolase ...
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Background: Meprin beta Subunit/MEP1B Meprins are multimeric proteases composed of alpha and beta subunits, which are members of the astacin family of zinc endopeptidases (1, 2). Both subunits form disulfide-linked homo- or heterooligomers, which are also referred to as meprin A (composed ...
Köhler D, Kruse M, Stöcker W, Sterchi EE. Heterologously overexpressed, affinity-purified human meprin alpha is functionally active and cleaves components of the basement membrane in vitro. FEBS Lett. 2000; 465 (1):2–7. doi: 10.1016/S0014-5793(99)01712-3. [ Cross Ref ]...
The meprin alpha subunit, a multidomain metalloproteinase, is synthesized as a type I membrane protein and proteolytically cleaved during biosynthesis in the endoplasmic reticulum (ER), consequently losing its membrane attachment and COOH-terminal domains. The meprin alpha subunit is secreted as a ...
oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefS...