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Introduction DNA is the vital carrier of genetic information in all living cells, but its chemical stability is affected by several factors. In fact, DNA is highly susceptible to chemical modifications by exogenous agents such as ionizing radiation and ultraviolet light [1–...
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The past decade has seen dramatic progress in our understanding of membrane contact sites (MCS). Important examples of these are endoplasmic reticulum (ER)-mitochondria contact sites. ER-mitochondria contacts have originally been discovered in mammalian
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Overview of ER-mitochondria lipid flux in yeast and mammalian cells. The location of synthesis for phosphatidylserine (PS), phosphatidylethanolamine (PE), phosphatidylcholine (PC), phosphatidic acid (PA) and cardiolipin (CL) are shown. Transport pathways (known:black; suspected:grey), as well as ...