The ratios of saturated fatty acids to unsaturated fatty acids increased in both human and mouse cells. The increase was also confirmed in the plasma membrane fraction of SPM-3T3 cells. Membrane fluidity was examined using a 1, 6-diphenyl-1,3,5-hexatriene (DPH) fluorescent probe. The DPH ...
The ratios of saturated fatty acids to unsaturated fatty acids increased in both human and mouse cells. The increase was also confirmed in the plasma membrane fraction of SPM-3T3 cells. Membrane fluidity was examined using a 1, 6-diphenyl-1,3,5-hexatriene (DPH) fluorescent probe. The DPH ...
highly sensitive to variations in the physicochemical properties of the cell membrane[162]. While higher membrane fluidity gives a more favorable environment for ABCA1 function, trans acyl chains in the membrane adopt extended configurations similar to saturated acyl chains[163], thus reducing fluidity...
Interestingly, all identified SM and LPC species (which mainly contain saturated or monounsaturated acyl chains18) increased simultaneously in aged muscle (Fig. 1f, g and Supplementary Fig. 1f, g). In parallel, we evaluated PC acyl chain length. Changes in C18 and >C18 fatty acid levels ...
Subcellular membranes have complex lipid and protein compositions, which give rise to organelle-specific membrane packing, fluidity, and permeability. Due to its exquisite solvent sensitivity, the lipophilic fluorescence dye Nile Red has been used extensively to study membrane packing and polarity. Further...
Ahydrophobicmolecule (or region of a molecule) repels and is repelled by water. Some lipid tails consist of saturated fatty acids and some contain unsaturated fatty acids. This combination adds to the fluidity of the tails that are constantly in motion. Phospholipids are thus amphipathic molecules...
The results support the concept that saturated and cis-unsaturated fatty acids dissolve in different lipid domains and this in itself appears to be an important factor defining whether the biological function of the membrane is affected by the uptake. Incorporation of cis-unsaturated fatty acids in ...
cis/trans isomerization of unsaturated fatty acids as possible control mechanism of membrane fluidity in Pseudomonas putida P8 来自 国家科技图书文献中心 喜欢 0 阅读量: 42 作者:B Loffeld,H Keweloh 摘要: Exponentially growing cells of Pseudomonas putida had an increased ratio of saturated to ...
For example, membrane rigidity also requires the involvement of saturated or unsaturated fatty acids to maintain or modify lipid phase order. And for synaptic vesicles, changes in number were likely confined by the sizes of the different vesicle pools. As only a subpopulation of synaptic vesicles ...
Further age-related changes in microvillus membrane lipid composition were characterized by a significant reduction in the weight ratio of saturated to unsaturated fatty acids in jejunum and ileum and by the emergence, in the mature animal, of a jejunal-ileal difference in total lipid content (...