As cPRC1 complexes all contain a Chromo domain protein PC-CBX homolog, which can recognize the specific methylation mark, the mechanism of PcG-dependent repression seemed simple. First, the H3k27 trimethylation mark is made by PRC2, and then it is recognized by PRC1. However, everything is...
As cPRC1 complexes all contain a Chromo domain protein PC-CBX homolog, which can recognize the specific methylation mark, the mechanism of PcG-dependent repression seemed simple. First, the H3k27 trimethylation mark is made by PRC2, and then it is recognized by PRC1. However, everything is...