Process temperatures are kept between the melting point of the instable α- and stable β-form, in the area where the direct recrystallization of the stable β-form predominates over the β′-form (205). This prevents the formation of fractal structures (159) and the alteration of the dissolu...
These were the same as those used in a previous paper.3 They are designated PEG 600, PEG 1000, and PEG 6000. Their molecular weights M are indicated in Table I. It was shown that these had narrow distributions of molecular weights. The sample of poly(tetrahydrofuran) used also had a ...
Swelling, melting point reduction and solubility of {PEG}1500 in supercritical {CO}_{2}ScPasquali, IComi, LPucciarelli, FBettini, RPASQUALI I,COMI L,PUCCIARELLI F,et al.Swelling,melting point reduction and solubility of P EG 1500 in supercritical CO2[J].International Journal of Pharmace...
The low melting point copolyester is made from the following monomers followed by the esterification reaction and the polycondensation reaction: (a) terephthalic acid (PTA) and isophthalic acid (IPA), (b) 1, 4- butanediol (BDO) and (c) polyethylene glycol 600 to 6000 (PEG); wherein, in ...
This study aimed to prepare a sustained-release solid dispersion of poorly water-soluble resveratrol (RES) with high melting point in a single hot melt extrusion step. A hydrophobic鈥揾ydrophilic polymeric blend (Eudragit RS and PEG6000) was used to control the release of RES. With the ...
This study aimed to prepare a sustained-release solid dispersion of poorly water-soluble resveratrol (RES) with high melting point in a single hot melt extrusion step. A hydrophobic鈥揾ydrophilic polymeric blend (Eudragit RS and PEG6000) was used to control the release of RES. With the ...
This study aimed to prepare a sustained-release solid dispersion of poorly water-soluble resveratrol (RES) with high melting point in a single hot melt extrusion step. A hydrophobic–hydrophilic polymeric blend (Eudragit RS and PEG6000) was used to control the release of RES. With the dispersive...