Prognosis of stage I melanoma of the skin. Int J Cancer 1980; 26: 733–9Cascinelli N, Morabito A, Bufalino R et al. (WHO collaborating centres for evaluation of methods of diagnosis and treatment of melanoma) (1980) Prognosis of Stage I melanoma of the skin. Int J Cancer 26:733–739...
BackgroundWe reviewed a contemporary, single-institution experience to evaluate the natural history of stage-IV melanoma metastatic to the l... Heather,B.,Neuman,... - 《Annals of Surgical Oncology》 被引量: 112发表: 2007年 Prediction of recurrence and prognosis in patients with hepatocellular ...
SLN mapping was performed on 592 patients with stage I and II malignant melanoma from March 1, 1994, through December 31, 1999. One hundred four patients were found to have 134 sentinel SLNs containing metastatic melanoma. The slides were reviewed, and the size of the metastatic melanoma in ...
To identify primary melanoma prognosis regulators, we examined the intersection between the previously identified top ten modules’ hub genes and the poor prognosis signatures (Fig.3A). This scheme nominated 18 regulators, which were more likely to be essential for melanoma cell viability than the po...
stage III or IV metastatic melanoma and to compare our results with published literature.Data were retrieved from three large, randomized, controlled trials of the European Organisation for Research and Treatment of Cancer in patients with stage III and two trials in patients with stage IV melanoma...
Melanoma has the highest propensity among solid tumors to metastasize to the brain. Melanoma brain metastases (MBM) are a leading cause of death in melanoma and affect 40–60% of patients with late-stage disease. Therefore, uncovering the molecular mechanisms behind MBM is necessary to enhance th...
(ATG5) helps to overcome BRAF-induced senescence to promote the malignant transformation of early-stage melanoma.228,229Besides, the deficiency of autophagy also facilitates tumor metastasis by stabilizing Twist family BHLH transcription factor 1 (TWIST1) protein through p62 accumulation.230These reports...
American Joint Committee on Cancer Classification of Uveal Melanoma (Anatomic Stage) Predicts Prognosis in 7731 Patients: The 2013 Zimmerman Lecture Results Of 7731 patients with posterior uveal (ciliary body and choroidal) melanoma, the AJCC tumor staging was stage I in 2767 (36%), stage II in...
1591 Accesses 1 Altmetric Metrics details Abstract Melanoma is a skin cancer with great metastatic potential, which is responsible for the major deaths in skin cancer. Although the prognosis of melanoma patients has been improved with the comprehensive treatment, for patients with metastasis, the ...
The development of molecularly targeted therapies such as the BRAFi vemurafenib or dabrafenib3,4and especially the combined BRAF and MEK inhibition improved the prognosis for BRAF-mutated metastatic melanoma patients5. Nevertheless, the majority of patients show progressive disease even after combined inhib...