I've looked at a bunch of melanoma pictures, and my mole doesn't look like any of them, but I'm still really paranoid about it. Is it possible to have a malignant melanoma or skin cancer if you have a mole that doesn't fit the ABCD standard? I'm really not very up on my skin...
In clinical work, melanoma is usually divided into different subtypes depending on the primary tumor site. These include CM, which occurs in the skin; AM, which arises from hairless skin on the palms, soles, and nail beds; UM, which develops from melanocytes in the uvea of the eye; and ...
Conclusion: This is the first report on an integrin/wnt signalling activation axis addressing the consequences for chemotherapy sensitiveness of melanoma cells, which thus offers novel therapeutic targets for approaches to interfere with chemoresistance. Keywords: chemoresistance; cisplatin; integrin; melanoma...