Resistance to ERK signaling inhibitors in BRAFV600E-mutant melanomas and lung cancers is achieved by parallel convergent mechanisms, including amplification of the mutant allele in extrachromosomal elements, tha
Basal cell skin cancerCancerDepigmentationLeukodermaMelanomaNonmelanoma skin cancerPhototherapySkin cancerSquamous cell skin cancerVitiligoThe relative genetic and immune protection against melanoma and nonmelanoma skin cancers in those with vitiligo is reassuring. The results of recent studies allow us to be ...
The OncLive Melanoma & Skin Cancer condition center page is a comprehensive resource for clinical news and expert insights on various types of skin cancers, including melanoma, basal cell carcinoma, and more. This section features news articles, interviews in written and video format, and podcasts ...
In most cases, melanoma is caused by exposure to ultraviolet (UV) radiation from the sun or tanning beds. It damages the DNA of your skin cells, and they start to grow out of control. You can get the disease on parts of your body that don't get sunlight, though, like the palms of...
Melanoma is the most aggressive and deadliest type of skin cancer. In the last 10 years, immune checkpoint blockades (ICBs) including PD-1/PD-L1 and CTLA-4 inhibitor has been shown to be effective against melanoma. PD-1/PD-L1 and CTLA-4 inhibitors have s
Cutaneous malignancies affect millions of people worldwide. These cancers cover a wide clinical spectrum, from relatively indolent types, such as the most common form of cancer basal cell carcinoma, to more lethal ones, such as melanoma. In this chapter
Nonablative fractional laser resurfacing can deliver aesthetic benefits to patients and may also prevent nonmelanoma skin cancer, according to an expert. May 23, 2025 3 min read Save Q&A: Changes in moles during pregnancy should not be ignored ...
Melanoma skin cancer is only ∼1% of total diagnosed skin cancers, but it causes majority of skin cancer-related deaths due to its high metastatic properties. Incidence of melanoma skin cancer increases in regions closer to the equator, with highest reported rates in Australia/New Zealand and ...
Melanoma is the most lethal skin malignancy, driven by genetic and epigenetic alterations in the complex tumour microenvironment. While large-scale molecular profiling of melanoma has identified molecular signatures associated with melanoma progression,
Sir, We read with great interest the article by RC Gerring et al 1 regarding prognostic factors and survival rates in a retrospective case series of patients who underwent orbital exenteration for non-melanoma skin cancers (NMSC). The authors have thoroughly described the correlation between ...