The decision to enter the meiotic cell cycle is made in G1 phase and this affects the way in which the G1–S transition is controlled. In budding yeast, nutrient limitation culminates in the expression of two principal regulators of meiotic initiation, inducer of meiosis (IME)1 and IME2,...
ovulation rate of pacu, Piaractus mesopotamicus, using hypophysation with prostaglandin F2α (PGF2α) (HPG protocol) rather than hypophysation (H); only, however, a persistent lack of ovulation in some females could not be further explained by PGF2α and steroid plasma levels at time of ...
The proportions of DMC1- and ATR-positive cells increase upon treatment.aSpreads from control and ATZ-treated mice were stained with anti-DMC1 (red) and anti-SYCP3 (green). In control mice, the DSBs are repaired at this stage, such that no DMC1 foci are detectable. In ATZ-treated samp...
DNA lesions threaten genomic integrity by interfering with a wide range of cellular processes, such as DNA replication, DNA transcription, and chromosome segregation1. Improperly repaired DNA lesions ultimately lead to genomic rearrangements, a hallmark of cancer cells2. DNA double-strand breaks (DSBs)...
The meiotic cell cycle continues and centromeric cohesins are lost, allowing the chromosomes to segregate during meiosis II (top right panel). Thus, mam1Δ mutants delay in metaphase I for 1–2 hr, the time it takes cells to progress from metaphase I to metaphase II. This delay is ...
This intermediate output is used by SPoRE to provide four kinds of data: 1. It produces the curves modeling the density of DSBs and axis proteins along the whole genome, in a format that is ready for browsing (see Additional file 1: Figure S1). 2. Given a list of intervals on the ...
We confirmed that this effect could not be explained by generally delayed meiotic progression in ama1Δ cells (Figures S1C, S1D, S1M, S1N) and further compared to a protein, Stu2, which has a similar overall protein pattern to the other candidates but was not in the same discrete sub...
LAB-1 Targets PP1 and Restricts Aurora B Kinase uponEntrance into Meiosis to Promote Sister ChromatidCohesionYonatan B. Tzur1, Carlos Egydio de Carvalho1¤, Saravanapriah Nadarajan1, Ivo Van Bostelen1,Yanjie Gu1, Diana S. Chu2, Iain M. Cheeseman3, Monica P. Colaia´covo1*1Department ...
1. The somatic chromosome complements of forms ofPaeonia show that there are variations in the morphology of the complements and that polyploidy occurs. 2. The average chiasma frequency at metaphase is low (1·3 per bivalent) and very little terminalisation occurs. 3. All but three of the...
10.1038/ncomms6070 OPEN Chiasmatic and achiasmatic inverted meiosis of plants with holocentric chromosomes Gabriela Cabral1,2,*, Andre´ Marques1,*, Veit Schubert3, Andrea Pedrosa-Harand1 & Peter Schlo¨gelhofer2 Meiosis is a specialized cell division in sexually reproducing organisms before ga...