Bernardi F, Pluchino N, Pieri M, Begliuomini S, Lenzi E, Puccetti S, Casarosa E, Luisi M, Genazzani AR. Progesterone and medroxy- progesterone acetate effects on central and peripheral allo- pregnanolone and beta-endorphin levels. Neuroendocrinology 2006;83(5-6):348-359¨....
Medroxyprogesterone acetate是一种孕激素,是一种人体孕激素的人工合成的变体,是有效的孕激素受体激动剂。 靶点(IC50 & Targe) ER PR 体外研究 Medroxyprogesterone acetate(MPA)抑制酶3- hydroxyste-固醇脱氢酶,参与(THP)5alpha-dihydroprogesterone(DHP)和3α,5alpha-tetrahydroprogesterone之间的可逆转换,因此,可能会影...
20-dione (dexamethasone; DEX, D4902), 6α-methyl-17α-hydroxy-progesterone acetate (medroxyprogesterone acetate; MPA, M1629), 4-pregnene-3,20-dione (progesterone; P4, P0130), 17α-ethynyl-19- nortestosterone (norethisterone; NET, N4128), and 11β-(4-dimethylamino) phenyl-17β-hydroxy-17...
We investigated the effects of progesterone (P), medroxyprogesterone acetate (MPA), drospirenone (DRSP) and nestorone (NES) alone or with 17β-estradiol (E2) on T47-D breast cancer cell migration and invasion and we linked some of these actions to the regulation of the actin-regulatory prote...
Medroxyprogesterone Acetate (Medroxyprogesterone 17-acetate Hydroxymethylprogesterone acetate;17alpha-Acetoxy-6-alpha- methylpregn-4-ene-3,20-dione; 17a-Hydroxy-6a-methyl-4- pregnene-3,20-dione acetate; Depo-provera),USD,0/Kilogram,cas No:71-58-9,Formula
as well as an increased risk ofdementiain the women over age 65. Therefore, medroxyprogesterone should not be used for thepreventionofheart diseaseor dementia. Although medroxyprogesterone alone has not been demonstrated to promote breastcancer, since breast cancerhas progesterone receptors, physicians us...
and require dynamic cytoskeletal and cell membrane rearrangements for cell motility to be enacted.We investigated the effects of progesterone (P), medroxyprogesterone acetate (MPA), drospirenone (DRSP) and nestorone (NES) alone or with 17beta-estradiol (E2) on T47-D breast cancer cell migration ...
Medroxyprogesterone acetate (Synonyms: 醋酸甲羟孕酮; Medroxyprogesterone 17-acetate; Farlutin) 纯度: 99.88% Medroxyprogesterone acetate 是一种广泛使用的合成类固醇,与孕酮 (progesterone),雄激素 (androgen) 和糖皮质激素受体 (glucocorticoid receptors) 都有作用。 Medroxyprogesterone acetate Chemical Structure CAS...
DEPO-PROVERA Sterile Aqueous Suspension contains medroxyprogesterone acetate, which is a derivative ofprogesteroneand is active by theparenteraland oral routes of administration. It is a white to off-white, odorless crystalline powder, stable in air, melting between 200° and 210° C. It is freely...
BACKGROUND: Depot medroxyprogesterone acetate (DMPA) is a very popular hormonal contraceptive. Unpredictable bleeding disturbances are the main reasons for discontinuation and may be mediated through endometrial hormone receptors. This study was aimed to compare the expression of progesterone and estrogen re...