A medium spiny neuron (MSN) is a type of inhibitory interneuron found in the striatum, characterized by medium-sized cell bodies and spiny dendritic arbors. MSNs receive excitatory inputs from the neocortex and thalamus, and send inhibitory outputs to the basal ganglia, as well as intrastriatal...
Medium Spiny Neurondoi:10.1007/978-3-540-29678-2_3380A type of central nervous neuron comprising more than 95% of the neurons in basal ganglia input structures, such as the caudate nucleus, putamen, nucleus accumbens and striatal districts in the...Springer Berlin Heidelberg...
Thus, despite possessing the same neuron type, striatal regions exhibit heterogeneity in sex differences in MSN electrophysiological properties, which likely contribute to the sex differences observed in striatal function. 展开 关键词: sex estradiol hormones striatum medium spiny neuron nucleus accumbens ...
Medium spiny neuronsSimple modelStriatal medium spiny neurons (MSNs) constitute input nuclei of the basal ganglia. Most well-known dichotomous of striatal MSNs stem from dopaminergic modulation of striatal processing. Dopamine moduldoi:10.1007/978-3-319-44778-0_30Sami Utku Çelikok...
1)Medium spiny neuron中等有棘神经元 1.Medium spiny neurons are the main cell type in nucleus accumbens, which takes up about 90% - 95% of the total cell amount.信息整合后通过中等有棘神经元支配基底神经节的传出结构来影响自主行为。 2)propriospinal neuron固有神经元 1.Describe the pathwayand ...
We also attempt to organize the data into common mechanisms that may arise outside the medium, spiny neuron, but ultimately have their greatest impact in the striatum. 展开 关键词: Huntington’s disease Cell-autonomous Medium size spiny neuron DARPP-32 BDNF ...
Dopaminergic modulation produces a variety of functional changes in the principal cell of the striatum, the medium spiny neuron (MSN). Using a 189-compartm... JT Moyer,JA Wolf,LH Finkel - 《Journal of Neurophysiology》 被引量: 128发表: 2007年 Analysis of neostriatal medium spiny neuron dendr...
Homeobox Gene Six3 is Required for the Differentiation of D2- Type Medium Spiny Neurons Medium spiny neurons (MSNs) in the striatum, which can be divided into D1 and D2 MSNs, originate from the lateral ganglionic eminence (LGE). Previously, we... X Song,H Chen,Z Shang,... - 《...
2005. Partial mitochondrial inhi- bition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP deple- tion. J Neurosci 25:10029-10040. L Bao,MV Avshalumov,ME Rice - 《Journal of Neuroscience the Official Journal of the Society for Neurosc...
Characterising the developmental profile of hESC-derived medium spiny neuron progenitors and assessing mature neuron function using a CRISPR-generated human DARPP-32 WT/eGFP-AMP reporter linedoi:10.1016/j.neuint.2017.01.003In the developing ventral telencephalon, cells of the lateral ganglionic eminence...