Electronic health records hold immense potential for providing clinically useful insights for populations and individuals; this Review summarizes the opportunities and challenges, with an emphasis on recognizing and reducing bias. Alice S. Tang , Sarah R. Woldemariam & Marina Sirota Research Highlight...
Forensic medicine deals with offenses against the person or patient. Practitioners of forensic medicine assist in medical-legal investigations by offering expert opinions to help legally authorized individuals understand the medical implications of pathological examinations, including postmortem examinations (autop...
now report their study of the evolution of a broadly neutralizing antibody response targeting a glycan on the viral envelope in two HIV-1–infected individuals. Their findings show that the targeted glycan is absent early in acute infection but develops over time as the virus escapes initial ...
Stroke is a common neurological disorder that disproportionately affects middle-aged and elderly individuals, leading to significant disability and mortality. Recently, human blood metabolites have been discov... Tianlong Zhang, Yina Cao, Jianqiang Zhao, Jiali Yao and Gang Liu ...
Such applications are likely to be most relevant at the public health and population level and not in the context of 'boutique' medicine benefiting individuals, and should address both the curative and preventive aspects of public health strategies. Complex challenges exist for effectively integrating ...
by developing relevant adaptive features needed for environmental survival. at the same time, after exposure to adversity, these same individuals also perform poorer in other outcomes that are not essential to basic survival in ...
Eugenics of the time deemed feeble-mindedness a matter of heritable germ plasm, hence a family trait. It followed that assessment of individuals for coercive sterilization typically entailed investigation of family members. Buck’s mother, it turned out, was also “defective” and had resided in ...
Truth claims in the medical literature rely heavily on statistical significance testing. Unfortunately, most physicians misunderstand the underlying probabilistic logic of significance tests and consequently often misinterpret their results. This near-un
third immunization (Fig.1b). Serum and vaginal IgA anti-trimer antibodies were also detected (Fig.1c). While the IgG responses were comparable between the immunization groups in both compartments, the IgA responses were moderately higher in the HVV + SOSIP/3M-052 group at some time ...
The individuals listed at the end of the paper are members of Working Groups that contributed to the writing of the LifeTime Strategic Research Agenda (listed in full in the Supplementary Information). Please note that the complete LifeTime Community is much broader and includes many associates ...