5 A health care delivery system equitable and accessible to all must be built on knowledge that is based on the experiences of, and relevance to, all. Third, the digital revolution in health care provides a data infrastructure on which practice and trials could be integrated. What Needs...
The ONNX weights of the model, as well as the normalization pipeline for the NMR data as fitted on the UK Biobank, are available through our GitHub repository (Code availability). Whitehall II Cohort The Whitehall II Cohort (WHII) is an ongoing prospective cohort study of adults, ...
The progressive advancement of artificial intelligence (AI) has garnered substantial attention and development in recent years, showcasing its efficacy in diverse practical applications such as autonomous driving, recommendation systems, and more. Notably, the data-centric approach inherent in AI methodolog...
Primary diabetes care and diabetic retinopathy (DR) screening persist as major public health challenges due to a shortage of trained primary care physicians (PCPs), particularly in low-resource settings. Here, to bridge the gaps, we developed an integrated image–language system (DeepDR-LLM), comb...
RNA sequencing (RNA-seq) is increasingly being used as a complementary tool to DNA sequencing in diagnostics where DNA analysis has been uninformative. RNA-seq enables the identification of aberrant splicing and aberrant gene expression, improving the interpretation of variants of unknown significance (...
DeepTrace: https://github.com/Bamrock/DeepTraceBackground Cancer is a leading cause of death, with an estimated 19.3 million new cases and nearly 10 million deaths worldwide in 2020 [1]. Among these, hepatocellular carcinoma (HCC) is one of the most common and deadliest types of liver can...
in a cancer type-dependent manner. Utilizing the expression matrices of these genes, we built models to quantitatively evaluate the malignant levels of tumors across cancers, which could add value to the clinical staging system for improved prediction of patients’ survival. Furthermore, we performed...
2 and 4 can be found in above de-identified tabulated data in github repository, and the exact p-values presented in Fig. 5 can be found in the Supplementary Tables 5 and 7. Code availability The R-based custom code for model training, statistical analysis, and generating Figs. 1–7 is...
2b, c). We expect that similar limitations will apply to many studies performed in pediatric settings and emphasize the importance of controlling for the time window when individuals received care within the health-care system. In our study, we refer to this window of health-care utilization as...
For this purpose, we made scDrugPrio into an easy-to-use R package (https://github.com/SDTC-CPMed/scDrugPrio).Background Immune-mediated inflammatory diseases (IMIDs), such as rheumatoid arthritis, Crohn’s disease, and psoriatic arthritis, affect millions of people worldwide and can cause...