Download PDF Editorial Summary Cancer: exploring the potential of exosomes Exosomes, membrane-bound vesicles released by some cells, contain a cargo of proteins and other biomolecules that can be analyzed to assist the diagnosis of cancer or predict its likely outcome, and may become useful in ...
The overall genome-wide average methylation ratios of HCC tumor tissues were significantly lower than those of corresponding para-tumor tissues (p-value < 0.01). Moreover, 39 out of 42 HCC patients showed that the genome-wide average methylation ratio of a tumor tissue was lower than that...
Deep learning (DL)-based predictive models from electronic health records (EHRs) deliver impressive performance in many clinical tasks. Large training cohorts, however, are often required by these models to achieve high accuracy, hindering the adoption o
When mammals evolved, another survival challenge joined the microbial threat and the predation fears shared by all vertebrates. Since the hallmark of the mammalian behavioral survival strategy is secure attachment to parental and social objects largely mediated by a part of the paralimbic cortex called...
Right parasternal bicaval view (obtained with the probe parallel to the sternal border with the marker cephalad) showing the advancement of the new drainage cannula over the wire. Panel B: final position of the new drainage cannula with the tip at the superior vena cava-right atrium junction....
A small cross peak was observed between H2 and H2’6′ thus supporting the point of attachment of one para-substituted phenolic ring. From the NOESY, H3 showed cross peaks to Hα and Hβ as well as H2’6′. This supported the connectivity of C3-O-C = O-α-β. Hβ revealed cross...
Estimates of the economic burden of CKD vary depending on whether dialysis and transplant therapies are included or excluded. Regardless, it is clear that CKD is a key driver of the high costs associated with NCDs. One report, using provincial data in a Canadian province, described that of a...
many practitioners at hospital pharmacies have to manually scan such codes one by one, a very repetitive and burdensome task. In this paper, a system which can simultaneously scan multiple Data Matrix codes and autonomously introduce them into an authentication database is proposed for the Hospital...
The primary end point (in hospital all-cause mortality) occurred in one patient (2.2%) in the normal CONUT score group, four patients (3.6%) in the mild CONUT score group, 20 patients (13.4%; vs. ‘normal’, p = 0.002; vs. ‘mild’, p = 0.007) in the moderate–high CONUT score...
(Comité de Ética de Protocolos de Investigación del Hospital Italiano de Buenos Aires), Chile (Comité de Ética del Servicio de Salud Araucanía Sur, Universidad de la Frontera), Uruguay (Comité de Ética para Proyectos de Investigación de la Universidad de la República) and US (...