Neither amlodipine nor felodipine increases cardiovascular morbidity or mortality in patients with HF.30,31 However, neither have they demonstrated benefit when compared with placebo in this patient population.
77 Notably, another study conducted in patients who developed myocarditis during therapy with an immune checkpoint inhibitor (an uncommon but well described unwanted effect of these chemotherapeutics78,79), not only found a decrease in GLS in those patients, but also that a lower GLS was ...
Main Outcomes and Measures The outcomes of interest were the composite of CV death or hospitalization for HF (HHF), HHF alone, and a kidney-specific composite outcome (persistent ≥40% decrease in estimated glomerular filtration rate [eGFR], end-stage kidney disease, or kidney-related death). ...
Auditory oddball task: MPH maintained SCL constant throughout the task in ADHD (up-regulation of arousal), while the decrease of SCL with task ongoing was larger in unmedicated ADHD, than controls.Resting state: An increase in ns-SCR amplitude revealed in unmedicated ADHD subjects during rest...
The goals of glaucoma therapy for the patient and the physician are ultimately the same ones, but they are often approached from very different perspectives. Most patients with glaucoma visit their ophthalmologist on a regular basis because they understa
an increase of 10% in the average percentage optimal dose was associated with a reduction in 180-day HF readmission or all-cause death (primary end point: adjusted hazard ratio [aHR], 0.89; 95% CI, 0.81-0.98; P = .01) and a decrease in 180-day all-cause mortality (aHR, 0.84;...
Iti , IK Ang II also increases the delayed rectifier potassium (IK), transient inward (Iti), pacemaker, and sodium-calcium exchanger (INCX) currents in pulmonary vein cardiomyocytes, whilst AT1 antagonists, such as losartan, decrease the Ito, Ik, Iti, and INCX currents [8]. INa Ang-(1...