Children admitted to the pediatric intensive care unit (PICU) often require multiple medications to achieve comfort and sedation. While starting doses are available, these medications are typically titrated to the desired effect. Both oversedation and undersedation are associated with adverse events. ...
Such concerns are not trivial since many patients in need for weight loss intervention are elderly, and muscle size and strength declines by 10–15% every decade after the age of 50 years.122 Nonetheless, it is important to note that a loss of FFM (often referred to as lean mass) is ...
Accordingly, we cannot rule out that these interesting results are due to chance. It is a common phenomenon that progressive improve- ment is seen following repeated cognitive function battery administration (Kantrowitz et al, 2009). In this study, significant time main effects detected for a ...
GABACreceptors are also ligand-gated ionotropic channels that are largely found in the retina. When activated by GABA, they evoke a Cl−current [42]. In contrast to GABAAreceptors, GABACreceptors, defined by the presence of a ρ subunit, are insensitive to the convulsant bicuculline [42]. ...
Johnson et al (2008) used FFT analysis of RTs from the SART (see above) and showed that treatment with medication (and average titrated dose of 0.51 mg/kg) over 6 weeks produced a decrease in the fast component of variability of RT. In summary, we should emphasize that one of the ...
These are almost universally commenced and titrated by visiting nurses. Prescribed medications are commonly used to help manage last-days-of-life symptoms. However, a minority of patients had medications started weeks or months before death for recorded reversible non-end-of-life care conditions. ...
Often the nerve fibers that make up a nerve are all individually wrapped in myelin, a protective sheath that causes electric impulses to conduct down the nerve much faster than fibers that lack myelin. (The same principle is used to improve electric wires by covering them with a plastic outer...
that fail to respond to other medications* Increases GABA[ILLUSTRATION OMITTED]Side effects: sedation behavioral and cognitive impairment, drowsiness, ataxia; personality and behavioral change in children-hyperactivity, blurred vision aggressiveness, and irritability (usually dose-related)* Titrated slowly-...
Intrathecal (IT) pumps are a critical part of cancer pain treatment. While there are currently three medications (morphine, ziconotide, and baclofen) approved by the Food and Drug Administration (FDA) for intrathecal drug use, there are other medications that can help provide pain relief. The ...
13 Moreover, some families may believe that commencing an opioid infusion implies that the medical team is “giving up” on the patient. Although research has shown that opioids, titrated for symptom control at the end of life, are not associated with hastening death,14, 15 this has not ...