Clinicians caring for patients with dementia are often at a loss when trying to manage dementia-related behavioral disturbances pharmacologically because no drugs have been proven effective for this indication. Antipsychotics are commonly prescribed for these patients despite a US Food and Drug ...
Atypical antipsychotic agents (eg, aripiprazole, olanzapine, and risperidone) have been shown to improve some behavioral symptoms, including aggression, in patients with dementia, but also increase mortality compared with placebo. (SOR: A, based on consistent meta-analyses.) Haloperidol decreases aggress...
Previous studies have reported that the most frequently prescribed psychotropic medications for patients with dementia were antipsychotics [34, 46]; however in this study antidepressants were predominantly used. This finding merits further investigation, using a larger population. The underpinning knowledge ...
Design, Setting, and ParticipantsThis prospective, open-label, pragmatic randomized clinical trial, embedded in 2 large national health plans, was conducted from April 2022 to June 2023. The trial included patients with AD or ADRD and use of any of 3 drug classes targeted for...
The impact of providing care for physical health in severe mental illness on informal carers: a qualitative study 2024, BMC Psychiatry Understanding the burden and influencing factors in family caregivers’ medication assistance for patients with dementia: a survey study 2024, BMC Geriatrics Stakeholder...
TheU.S. Food and Drug Administrationrecently approved the drug brexpiprazole (Rexulti) for treating the agitation associated with Alzheimer's disease. "Agitation is one of the most common and challenging aspects of care among patients with dementia due to Alzheimer's disease. 'Agitation' can includ...
Gurwitz JH Start low and go slow: dosing of antipsychotic medications in elderly patients with dementia. Arch Intern Med 1995;1552017- 2018ArticlePubMedGoogle ScholarCrossref 16. Avorn JSoumerai SBEveritt DE et al. A randomized trial of a program to reduce the use of psychoactive drugs in ...
These drugs help in ministering to memory problems and mental instabilities. Often used by patients with some types of dementia and Alzheimer’s disease, cholinesterase inhibitors enhance memory function, judgment, and attention. On the flip side, a sharp increase in these activities impe...
Several recent articles question the benefit of percutaneous endoscopic gastrostomy (PEG) tube placement in persons with advanced dementia. However, patients with advanced dementia are still referred for PEG tubes. This study attempts to understand more about physician......
New treatment options for dementia and its behavioral disturbances have become available since publication of The Expert Consensus Guidelines on the Treatm... ECPF Dementia - 《Postgraduate Medicine》 被引量: 631发表: 2005年 Melatonin for Sleep in Children with Autism: A Controlled Trial Examining ...