ObjectiveTo explore the medication law and mechanism of traditional Chinese medicine compounds in the treatment of periodontal disease through data mining, network pharmacology, and molecular docking.MethodsFirst, data mining was used to search single medicinal materials for the treatment of periodontal dis...
Seven compounds were synthesized and evaluated for their antifungal activity against Candida albicans (ATCC 10231), Aspergillus fumigatus (HIC 6094), Trichophyton rubrum (IFO 9185) and Trichophyton mentagrophytes (IFO 40996). Among these compounds, 43 and 44 showed almost equal activity compared with...