Prolongation of this interval can lead to life-threatening complications. These can include arrhythmias such as Torsades de Pointes and Ventricular Fibrillation, which may ultimately lead to death. Many risk factors have been identified in prolonging the QT interval, one of which is medication ...
Background Prolongation of the corrected QT (QTc) interval is a key issue for patients who receive psychotropic medications. Such patients may have baseline clinical risk factors for QTc prolongation, and many psychotropic medications may further prolong this interval. This has great clinical relevance...
Risk of Serious Cardiovascular Problems with Medications for Attention-Deficit Hyperactivity Disorder ADHD and the risk of serious cardiovascular problems, specifically the risk of corrected QT interval (QTc) prolongation, and the risk of sudden cardiac ... J Martinez-Raga,C Knecht,N Szerman,... -...
Pharmacists must be vigilant about monitoring patients for drug–drug interactions that may increase their risk of QT prolongation and, potentially, TdP. By paying attention to patient medication lists, pharmacists may identify patients at risk for QT prolongation and progression to TdP. Patients receiv...
According to the FDA, Ingrezza is known to cause side effects such as sleepiness and can disturb cardiac rhythms (QT prolongation), and should be avoided by patients with certain cardiac conditions. Valbenazine's manufacturer, Neurocrine Biosciences, sponsored the study. In addition to Emory, othe...
QT prolongation • Rare but serious risk of sudden death • Use with caution in any condition with prolonged QT • Consider avoidance or dose ↓ Neuroleptic malignant syndrome • Rare but serious risk • Hyperthermia • Muscle rigidity • Altered mental status • Autonomic dysfunction ...
Cisapride, which is manufactured by Janssen Pharmaceutica, is approved for treating the symptoms of night time heartburn. The revised label states that 'QT prolongation, torsades de pointes (sometimes with syncope), cardiac arrest, and sudden death' have been reported in patients on cisapride who ...
There is no sound evidence for either treatment. Chloroquine has side effects (nausea, QT prolongation) and there are several drug interactions. The treatment should be reconsidered in the event of side effects and when inferior medication for comorbidity must be prescribed because of possible ...
acute episode. Ondansetron is typically well-tolerated though headaches, drowsiness, diarrhea, and constipation have been reported. A baseline electrocardiogram (EKG) to check for QT prolongation is generally recommended in adults prior to using ondansetron. As with other therapies in CVS, the oral ...
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