As alternative to injections, semaglutide can be administered orally. Semaglutide is already approved as an oral antidiabetic agent under the name Rybelsus, but not yet for weight loss. However, the OASIS 1 approval study showed a comparable average weight reduction to Wegovy, with 15% (or ...
In contrast, a randomized trial comparing UDCA and placebo with a combination of budesonide and UDCA showed the combination to be more effective, while bone thinning (loss of mineral density) was comparable in the two groups. But here again, more data are needed to confirm the benefit and ...