MEDICAL researchCOHORT analysisETIOLOGY of diseasesCAUSATION (Philosophy)RANDOMIZED controlled trialsBackground: Mediation analysis addresses the question of the mechanisms by which an exposure causes an outcome. This article is intended to convey basic knowledge of statistical mediation analysis. Methods: ...
This study extends previous research using Structural Equation Modeling (SEM) to include mediation analysis of the observed variables within the latent constructs of Cynicism (CY) and Inadequacy (IN) that are thought to influence the relationship between IPAL and ABO. Data were sourced from a valida...
Monotonic mediation analysis In what follows, unless otherwise stated, base models for means and covariances are based on the predictors I1 and I2, and so with only intercepts iM and iY for the means along with CSH covariance structure. Also assume p " = 1 unless otherwise indicated. 1. ...
In this issue ofJAMA, Lee et al1provide the results of a carefully structured, comprehensive effort to define the elements to be included in reports of studies using mediation analyses. Mediation analysis refers to a group of statistical methods for assessing the relative contributions of ...
Mediation analysis has been used to examine relations among a wide range of predictor and outcome variables in nutrition research. Within the American Journal of Clinical Nutrition (the Journal), genomic, proteomic, and metabolomic variables (e.g., serum lipid concentrations, specific genetic polymorph...
Mediation analysis was performed to determine whether the effect of TC on SBP can be explained by arterial stiffness. Multivariate linear regression analysis showed that for every one standard deviation increase in TC and BaPWV, SBP increased by 0.33 mmHg and 0.044 mmHg, respectively; for every ...
While our hypotheses and study findings are primarily derived from an analysis of the top 20 universities as ranked by the ARWU, this does not imply that these hypotheses and findings are not applicable to universities that are not listed in the ARWU or those below the first 20 positions. Rat...
The natural indirect effect (NIE) and mediation proportion (MP) are two measures of primary interest in mediation analysis. The standard approach for mediation analysis is through the product method, which involves a model for the outcome conditional on
Mediation analysis has emerged as a versatile tool for answering mechanistic questions in microbiome research because it provides a statistical framework for attributing treatment effects to alternative causal pathways. Using a series of linked regressions, this analysis quantifies how complementary data rel...
Specifically, a meta-analysis revealed a negative correlation between resilience and these negative mental health indicators31. Additionally, extensive research has confirmed the protective role of resilience in the mental health outcomes of medical staff. For instance, a systematic review highlighted ...