However, little attention has been paid to explaining such effects, probably because techniques for mediation analysis existing so far have not been applicable to survival data. Methods We investigated the underlying mechanisms using a recently developed method for mediation analysis of survival data. ...
Zhang H, Zheng Y, Hou L, Zheng C, Liu L. Mediation Analysis for Survival Data with High-Dimensional Mediators. Bioinformatics. 2021. DOI: 10.1093/bioinformatics/btab564. PMID: 34343267; PMCID: PMC8570823 Zhang H, Chen J, Feng Y, Wang C, Li H, Liu L. Mediation effect selection in hig...
Causal Mediation Analysis With Time-Varying and Multiple Mediators The survival mediational g-formula constitutes a powerful tool for conducting mediation analysis with longitudinal data.Finally, the third paper further ... SH Lin 被引量: 0发表: 2016年 ...
Although the causal steps procedure provides an elegant framework for conceptualizing mediation, there are critical limitations of the method when applied to real data analysis. The first limitation is the conclusion that there needs to be a significant relation between the predictor and the outcome ...
They suggested a tobit mediational model to account for censored data in the estimation of effects. However, as their approach was not in the context of causal mediation analysis no attention was given to assumptions about unconfoundedness or related sensitivity analyses. The mediation package (Tin...
Thus, mediation analysis allowing for multiple mediators would be less sensitive to model misspecification, and as a result im- prove the statistical power of the tests. Applied to the HapMap3 data, our approach allowing for multiple me- diators identified 11 mediated trans-eQTLs that were not...
Dr. Atanu Bhattacharjeeis a medical statistician the University of Leicester. He is an expert in the field of medical statistics, with a focus on survival analysis, competing risks, and high-dimensional data. Dr. Bhattacharjee’s research interests include the development of new statistical methods...
For instance, in fields like labor economics [14], epidemiology [15], and survival analysis [16], the data are sampled from individuals and essentially determined by personal characteristics, resulting in substantial high levels of nonlinearity, complexity and heterogeneity. This holds particularly ...
Introduced counterfactual framework for mediation analysis in the presence of interaction • med4way is the first Stata command for the decomposition of the total effect in mediating and interactive effects allowing for continuous, binary, count and survival outcome and for a continuous or binary ...
Marital status and survival in cancer patients: a systematic review and meta-analysis. Cancer Med. 12, 1685–1708 (2023). Article PubMed Google Scholar de Oliveira, C. M. et al. Relationship between marital status and incidence of type 2 diabetes mellitus in a Brazilian rural population: ...