Mediastinal lymph node sampling is critical to the initial diagnosis and staging of lung and esophageal cancers and lymphoma. Additionally, it is essential for detecting primary or recurrent nodal metastases in extrathoracic malignancies. This can be done by a variety of techniques employed by a vari...
Mediastinal Lymph Node Stations
ultrasound fine-needle aspiration (EUS-FNA) allows sampling of mediastinal lymph nodes relevant to lung cancer staging, particularly in the subcarinal area (station 7), lower para -esophageal lymph nodes (station 8), inferior pulmonary ligament lymph nodes (station 9), and celiac lymph nodes. ...
Subsequently, using the open or VATS approach, appropriate lung resection was performed and lymph node stations 5, 6, 7, 8, and 9 L were dissected. The dissection technique has been described in detail elsewhere [5]. During the procedure, the nodes from each station were labelled separately ...
Later we examined the impact of micrometastasis that is detected in more than one lymph node station in upstaged patients to N2 on the patients’ survival, as it is previously shown that multiple-station N2 has been correlated to worse survival [23]. We analysed patients who upstaged to N2...
The earlier studies on mediastinal lymph node (MLN) fine needle aspiration (FNA) were limited to endoscopic ultrasound (EUS)-FNA from the esophagus or relatively blind transbronchial needle aspiration. The smaller diameter endobronchial ultrasound (EBUS) scope came into practice few years after the EU...
[9]. Development of reactive granulomas in local lymph node groups draining the area occurs as tumor antigens are exposed to T cells after necrosis or tumor cell lysis. This can explain regional lymphadenitis but cannot explain the same phenomenon in remote lymph node groups. Similarly, systemic...
How many aspirations per target lymph node station? Chest. 2008;134:368–74. Article PubMed Google Scholar Nayak A, Sugrue C, Koening S, Wasserman PG, Hoda S, Morgenstern NJ. Endobronchial ultrasound-guided transbronchial needle aspirate (EBUS-TBNA): A proposal for on-site adequacy criteria....
Lymph node stationNmaxSUV range (median)NmaxSUV range (median)P value∗ 2 5 2.0–20.9 (7.2) 62 1.0–2.5 (1) <.001 4 12 2.2–25.8 (8.1) 327 1.0–9.6 (1) <.001 5 and 6 9 2.3–11.0 (7.1) 75 1.0–6.4 (1) <.001 7 5 7.1–10.0 (8.5) 172 1.0–6.8 (1) <.001 8 and ...
Therefore, unforeseen N2 (uN2) after pulmonary resection and lymph node dissection is to be avoided by strict compliance to the guideline. However, retrospective series from the United States, the Netherlands and Canada indicated that invasive mediastinal staging varied widely [[6], [7], [8]]...