Group 1 includes patients with platinum sensitive SCLC who will receive durvalumab (1500 mg given as an intravenous [IV] infusion once every 3 weeks) and topotecan (1.25 mg/m2/day IV for 5 consecutive days every 3 weeks). In Groups 2A and 2B, patients with platinum sensitive and platinum...
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575 to first-line carboplatin/paclitaxel (CP) chemotherapy.#The phase 1b component was a dose-escalation study combining MEDI-575 with carboplatin area under the plasma concentration versus time curve 6 and paclitaxel 200 mg/m2(CPM), with the end point of identifying a recommended phase 2 dose...
Liu Y, Zhang L, Zhu X, Wang Y, Liu W, Gong W (2015) Polysaccharide Agaricus blazei Murill stimulates myeloid derived suppressor cell differentiation from M2 to M1 type, which mediates inhibition of tumour immune-evasion via the Toll-like receptor 2 pathway. Immunology 146: 379-91. doi: ...
Dry-matter production, N, and K uptake by plant (g m2) were evaluated in the first and second trials. Salinity and NK nutrition levels significantly affected (P < 0.05) dry matter and N and K uptake by melon plant. Nitrogen and K uptake present interesting correlations with production and...
Dry-matter production, N, and K uptake by plant (g m2) were evaluated in the first and second trials. Salinity and NK nutrition levels significantly affected (P < 0.05) dry matter and N and K uptake by melon plant. Nitrogen and K uptake present interesting correlations with production and...
WOMEN HEALTH: -Metabolic syndrome, fractures and gender
HEART FAILURE: -Race/ethnic disparities in left ventricular diastolic function in a triethnic community cohort