mechanistic target of rapamycin complex 1 is an essential mediator of metabolic and mitogenic effects of fibroblast grow.机械的雷帕霉素靶1是一个重要的中介复杂的代谢和纤维母细胞生长 热度: Mechanistic assessment of DNA ligase as an antibacterial target in Staphylococcus aureus. 热度: Selective ...
This special issue on mammalian target of rapamycin (mTOR) explores the importance of mTOR in cell growth control and cancer. Cancer cells often exploit mTOR as a mechanism to enhance their capacity to grow. While protein synthesis is by far the best-characterized mTOR-driven process, this speci...
Mechanistic Target of Rapamycin (mTOR): Integrating Growth Factor and Nutrient Signaling in the Collecting Duct 来自 国家科技图书文献中心 喜欢 0 阅读量: 18 作者:B Aaron,MB Fluitt,CM Ecelbarger 摘要: The kidneys are a vital pair of bean-shaped organs in the lower back primarily involved in ...
The mechanistic target of rapamycin (mTOR) network is an evolutionarily conserved signaling hub that senses and integrates environmental and intracellular nutrient and growth factor signals to coordinate basic cellular and organismal responses, such as cell growth, proliferation, apoptosis, and inf...
Novel targets to arrest neurodegeneration in several dementing conditions involving misfolded protein accumulations may be found in the diverse signaling pathways of the Mammalian/mechanistic target of rapamycin (mTOR). As a nutrient sensor, mTOR has imp
篇名 Stem cell guidance through the mechanistic target of rapamycin 来源期刊 世界干细胞杂志:英文版(电子版) 学科 医学 关键词 Apoptosis AUTOPHAGY Cancer Cardiovas- cular Erythr 年,卷(期) 2015,(7) 所属期刊栏目 研究方向 页码范围 999-1009 页数 11页 分类号 R96 字数 语种 DOI 相关学者/机构...
Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythe... Perl, "Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+CD4-CD8- double-negative T cells and contracts regulatory T ...
We hypothesized that mechanistic Target of Rapamycin Complex 1 (mTORC1) is a positive regulator of key genes encoding Electron Transport Chain (ETC) proteins and stimulates oxidative phosphorylation in trophoblast and that ETC protein expression is down-regulated in placentas of infants with ...
Recent studies have demonstrated that the mechanistic/mammalian target of rapamycin (mTOR) pathway plays a critical regulatory role in the pathophysiology of antipsychotic drug-induced disorders of hepatic glucose and lipid metabolism. Furthermore, antipsychotic drugs promote striatal mTOR pathway activation ...