miR-146a is involved in inflammation by regulating immune cells Regulation of macrophages To be consistent regarding Th1 and Th2 differentiation paradigms for T cells, macrophage differentiation involved in the production of various phenotypes was divided into canonical M1 polarization and alternative M2 ...
Ventilator-induced lung injury (VILI) is one of the severe complications in the clinic concerning mechanical ventilation (MV). Capsaicin (CAP) has anti-inflammatory and inhibitory effects on oxidative stress, which is a significant element causing cellular ferroptosis. Nevertheless, the specific role ...
These findings suggest that this KPL-3C cell line may be useful for studying the regulatory mechanisms of PTHrP secretion and the mechanisms that lead to... J,Kurebayashi,M,... - 《British Journal of Cancer》 被引量: 75发表: 1996年 Ventilation and secretion of pulmonary surfactant Various ...
Biophysics Mechanisms underlying lung injury and inflammation following experimental mechanical ventilation THE JOHNS HOPKINS UNIVERSITY Sekhar P. Reddy BiermanAlexis Marie FisherMechanical ventilation (MV) is the cornerstone life-support therapy for ALI/ARDS patients; however, persistent health problems such ...
[110]. SAMHD1 occurs more frequently in severe ventilation-associated COVID-19 patients than in nonventilated patients [111]. SAMHD1 regulates the innate immune response and adaptive IFN activation [34,112]. Further research is still needed for the management of COVID-19 to study the ...
The NLRP3 inflammasome has also been implicated in a model of lung injury induced by mechanical ventilation. Interestingly, in this model of ventilator-induced lung injury, uric acid accumulated in the BAL fluid.74 A subsequent study implicated eATP, another known activator of the NLRP3 inflammaso...
[100]. In intensive care unit patients, lower serum gelsolin levels were correlated with a deceased chance of discontinuation from mechanical ventilation within 28 days. Furthermore, these patients were less likely to be discharged from intensive care by day 14 compared to patients with higher ...
Supportive therapy is mainly used for the current treatment of CMs, including maintaining normal body posture through corrective surgery, gastrostomy surgery for patients with dysphagia, regular testing of respiratory and cardiac functions, and timely non-invasive ventilation and coughing assistance for pati...
indicating ventilation issues and elevated PaCO2indicating gas exchange problems [20]. OI values < 300 mmHg suggest acute lung injury, < 100 mmHg may indicate ARDS. These assessments provide insights into lung conditions but do not fully capture cellular injury or predict disease outcomes,...
Dexmedetomidine in patients with sepsis requiring mechanical ventilation-reply. JAMA 318: 480. Article Google Scholar Chen, X., J. Hu, C. Zhang, Y. Pan, D. Tian, F. Kuang, and Z. Tang. 2018. Effect and mechanism of dexmedetomidine on lungs in patients of sepsis complicated with acute...