A concept of functional isolation of the heart from nervous effects as a mechanism of heart adaptation to extreme states has been formulated. In moderate hypoxia, isolation of the cardiovasomotor center from nonhypoxic afferention provides the compliance of myocardial hyperfunction to the intensity of...
Studies on the mechanism of electron trasport in the bc1-segment of the respiratory chain in yeast. III. Isolation and characterization of an antimycin res... 1. A mutant (ANT 8) of Schizosaccharomyces pombe which shows resistance to antimycin both in vivo and in vitro is characterized biochem...
P. IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones. Eur. J. Immunol. 11, 317–323 (1981). Article CAS PubMed Google Scholar Mackay, G. A. et al. Mutagenesis within human FcεRIα differentially affects human and murine...
the glycan component; no mechanism of protein specificity by this class of enzymes has yet been described. The Asn297-linkedN-glycan is required for IgG binding to Fc γ receptors (FcγRs) and complement C1q, which trigger antibody-mediated effector functions5,6,7,8. The activity of these ...
W Gilbert,D Dressler - 《Cold Spring Harbor Symposia on Quantitative Biology》 被引量: 368发表: 1968年 Mechanism of DNA chain growth: XVI. Analyses of RNA-linked DNA pieces in Escherichia coli with polynucleotide kinase An improved method for the isolation of RNA-linked DNA pieces from Escheric...
Multipass membrane proteins play numerous roles in biology and include receptors, transporters, ion channels and enzymes1,2. How multipass proteins are co-translationally inserted and folded at the endoplasmic reticulum is not well understood2. The preva
A Liver single-cell isolation, detection and analysis workflow in MCD-induced NASH and control mice (each group n = 3). B t-SNE visualization of clusters based on the single-cell transcriptome. A total of 21 single-cell clusters (0–20) and 5 single-LSEC clusters (0, 1, 5, 12...
Isolation and functional characterization of a new myotoxic acidic phospholipase A(2) from Bothrops pauloensis snake venom. This article reports the purification procedure and the biochemical/functional characterization of Bp-PLA 2, a new myotoxic acidic phospholipase A 2 from B... RS Rodrigues,LFM...
Bacterial pathogens have evolved intricate mechanisms to evade the human immune system, including the production of immunomodulatory enzymes. Streptococcus pyogenes serotypes secrete two multi-modular endo-β-N-acetylglucosaminidases, EndoS and EndoS2, t
Participation of lysosomes in cellular autophagy induced in rat liver by glucagon. J. Cell Biol. 35, C11–C16 (1967). Article PubMed PubMed Central CAS Google Scholar Tsukada, M. & Ohsumi, Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett....