Sulfonamides: structure-activity relationships and mechanism of action - Anand - 1983 () Citation Context ...ain glycogen. Sulfonamides are structural analogues and competitive antagonists of para-aminobenzoic acid (pABA), and thus prevent normal bacterial use of pABA for the de novo synthesis of ...
Tipranavir (formerly known as PNU-140690) is the first of a new class of nonpeptide protease inhibitors, the dihydropyrone sulfonamides. Tipranavir was developed and is marketed by Boehringer Ingelheim with the trade name Aptivuss. It was s
Sulfonamides Sulfones Sulfur Compounds Thiazoles Chemical TaxonomyProvided by Classyfire Description This compound belongs to the class of organic compounds known as benzothiazoles. These are organic compounds containing a benzene fused to a thiazole ring (a five-membered ring with four carbon atoms, on...
G01AE10 — Combinations of sulfonamides G01AE — Sulfonamides G01A — ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS G01 — GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS G— GENITO URINARY SYSTEM AND SEX HORMONESS01EC03 — Dorzolamide S01EC — Carbonic anhydrase inhibitors S01...
The sulfonamides are structural analogues of molecules and are similar to biological molecules normally used by the cell target. By using these pharmacological molecules, metabolic pathways of the organism are blocked, causing an inhibition in the production of nitrogen bases and eventually cell death....
Anticonvulsant Sulfonamides/Sulfamates/Sulfamides with Carbonic Anhydrase Inhibitory Activity: Drug Design and Mechanism of Action. The marketed antiepileptic drugs can not solve entirely the problem of seizure in patients suffering from refractory epilepsies. Therefore, new anticonvuls... Thiry,Anne,Dogné...
The sulfonamides (sulfas) were the first synthetic compounds deployed as antibacterial drugs. The broad-spectrum bacteriostatic activity of these chemicals against both Gram-positive and Gram-negative bacteria led to their use in both human and veterinary medicine world-wide11,12. However, as is the...
Then R, Angehrn P: Nature of the bactericidal action of sulfonamides and trimethoprim, alone and in combination. The Journal of Infectious Diseases. 1973, 128: 498-501. 10.1093/infdis/128.Supplement_3.S498. Article Google Scholar Then R, Angehrn P: Sulphonamide-induced 'thymineless death' ...
Many strains of Haemophilus influenzae are resistant to erythromycin alone but are found to be susceptible to erythromycin and sulfonamides used in combination. It is important to note that Staphylococci that are resistant to erythromycin may emerge during erythromycin and/or sulfonamide therapy.21 Pseudo...
Lignans, neolignans and related compounds / 2-phenylbenzofurans / Sulfanilides / Furan-3-carboxylic acid and derivatives / Fluorobenzenes / Aryl fluorides / Organosulfonamides / Organic sulfonamides / Heteroaromatic compounds / Aminosulfonyl compounds show 8 more Substituents 2-arylbenzofuran flavonoid ...