Erythropoietin interacts with its target cells through specific high-affinity receptors and Ca2+ may be involved in the receptor-ligand interaction. Ca2+ may also be involved in the induction of differentiation by erythropoietin. An increase in RNA synthesis due to activation of transcription is one ...
Erythropoietin is a recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia.
Erythropoietin The serum concentration of Erythropoietin can be decreased when it is combined with Captopril. Esmolol Esmolol may increase the hypotensive activities of Captopril. Esomeprazole Esomeprazole can cause a decrease in the absorption of Captopril resulting in a reduced serum concentration and po...
It involves inducing the expression of erythropoietin genes, such as gamma-globin, PGBD, erythropoietin receptor (EpoR), and overexpression of erythroid transcription factors, such as GATA-1 [31] (Fig. 3). Fig. 3 Molecular pathways initiated by aclarubicin Full size image Chemosensitization and...
These cells utilize the iron to synthesize heme, a vital component of hemoglobin. In the presence of erythropoietin, these progenitor cells mature into erythrocytes, leading to an increase in hemoglobin and, consequently, in red blood cell count, typically observed about seven days post iron-...
Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure CONCLUSION: VEGF is crucial for EPO-induced improvement of cardiac function in HF. EPO fosters VEGF expression predominantly in cardiomyocytes, which in turn... WB Daan,Ruifrok Wille...
Interleukin (IL)-1 is a pivotal pro-inflammatory cytokine and an important mediator of both acute and chronic central nervous system (CNS) injuries. Despit... E Pinteaux,P Trotter,A Simi - 《Cytokine》 被引量: 187发表: 2009年 Effects of Erythropoietin on Endothelin-1 Synthesis and the Cel...
Development of erythropoietin receptor-targeted drug delivery system against breast cancer using tamoxifen-loaded nanostructured lipid carriers Drug Des. Devel. Ther., 11 (2017), pp. 771-782 Google Scholar [64] T. Liang, Z. Yao, J. Ding, Q. Min, L. Jiang, J.J. Zhu Cascaded aptamers-gov...
[96]. PHD inhibitors upregulate iron regulatory proteins to improve iron absorption and increase the production of endogenous erythropoietin and enzymes involved in iron metabolism, thereby improving iron utilization [97]. Another study showed that the gene encoding DMT1 is regulated by HIF-2α [97...
Erythropoietin The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Thiotepa. Escitalopram The therapeutic efficacy of Escitalopram can be decreased when used in combination with Thiotepa. Esketamine The metabolism of Thiotepa can be increased when combined with Esketam...