Nieminen AL, Ramshesh VK, Lemasters JJ (2008) Use of fluorescent reporters to measure mitochondrial membrane potential and the mitochondrial permeability transition. In: Dykens JA, Will Y (eds) Drug induced mitochondrial dysfunction. Wiley, New Jersey, pp 414–431...
Mitochondrial integrity is essential for the regulation of cellular energy the regulation of apoptosis. Mitochondrial integrity can be measured with antibodies available in theMitochondrial Membrane Potential Assay Kit (II)and by examining biomarkers includingcytochrome C, which is released from mitochondria ...
Glutaminolysis and glycolysis regulation by troglitazone in breast cancer cells: Relationship to mitochondrial membrane potential. Journal of Cellular Physiology 226, 511–519 (2011). Article CAS Google Scholar Krall, A. S., Xu, S., Graeber, T. G., Daniel, B. & Christofk, H. R. ...
aThe histopathology of dopaminergic neuron, mitochondrial membrane potential, and the expression of autophagy-related and apoptosis-related genes and proteins from substantia nigra and striatum samples and PC12 cell 多巴胺能的神经元病理组织学、线粒体膜潜力和与autophagy相关和与apoptosis相关的基因和蛋白质表...
In parallel with the mitochondrial network redistribution, mitochondria switched to uncoupled respiration with a tendency towards decreased membrane potential, with no variation of mtTFA and NRF1 gene expression. The expression of PGC1α and NRF2 genes and genes involved in lipid oxidation (UCP2, CD...
Briefly, each sample was pre-processed based on RNA counts and mitochondrial read percentages and then normalized. The highly variable genes were then identified, followed by scaling and dimensional reduction via PCA. With the selected number of components, graph-based clustering and UMAP plotting ...
thaliana mitochondrial DNA Somatic Brassica napus (+) Arabidopsis thaliana hybrids with a cytoplasmic male sterility (CMS)-inducing cytoplasm were screened for fertility-restored... M Leino,S Thyselius,M Landgren,... - 《Theoretical & Applied Genetics》 被引量: 55发表: 2004年 Genotoxicity study ...
Turrens JF (2003) Mitochondrial formation of reactive oxygen species. J Physiol 552:335–344 Article CAS PubMed Central PubMed Google Scholar Halliwell B, Whiteman M (2004) Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the ...
Sphingomyelin synthases 1 and 2 convert the anti-oncometabolite ceramide to sphingomyelin, the most abundant sphingolipid in plasma membrane. CD95L-induced ceramide increase is associated with the caspase-dependent inhibition of sphingomyelin synthesis, which enhances the mitochondrial route to apoptos...
Increased production of reactive oxygen species (ROS) and deficiencies in cellular antioxidant defenses are the principal causes of cellular oxidative stress. ROS can react with a variety intracellular molecules, including redox active cysteine thiols (–SH) within proteins. Cysteine thiols can occupy se...