While 24 nt siRNAs resulted dramatically reduced in rmr6 mutant, long-term drought stress induces down-regulation of a very small number of siRNA loci in both wt and mutant leaves. Based on the analysis of our total RNA-Seq data, an improved annotation of the stress-responsive epigenetic-...
There has been considerable interest in discovery of the genetic architecture of complex traits, particularly age-related neurodegenerative disorders. To predict disease risk and to understand its genetic basis in humans, it is necessary to study animal
The invention is directed to a method of detecting gluten-induced diseases such as e.g. celiac disease and dermatitis herpetiformis. Said diseases are indicated by the presence of a
11,12. RNA-Seq has great sensitivity and a high base resolution capacity to discriminate between splicing variants, alleles and sense/antisense isoforms, allowing the identification
GFAP positive neural progenitors (NHA) derivatives differentiating to the neuronal lineage demonstrated silencing of glial and progenitor markers [GFAP, CD44, NESTIN] expression, while those differentiating to the glial lineage showed silencing of neuronal and progenitor markers [β-III-TUBULIN, MAP2, ...
GFAP positive neural progenitors (NHA) derivatives differentiating to the neuronal lineage demonstrated silencing of glial and progenitor markers [GFAP, CD44, NESTIN] expression, while those differentiating to the glial lineage showed silencing of neuronal and progenitor markers [β-III-TUBULIN, MAP2, ...
GFAP positive neural progenitors (NHA) derivatives differentiating to the neuronal lineage demonstrated silencing of glial and progenitor markers [GFAP, CD44, NESTIN] expression, while those differentiating to the glial lineage showed silencing of neuronal and progenitor markers [β-III-TUBULIN, MAP2, ...
For microsatellites, we estimated the mean number of alleles per locus (MNA), and the observed heterozygosity (Ho) and the expected heterozygosity (He) [61] were calculated for the overall sample studied. He values were arcsine transformed prior to statistical analysis [62]. Kruskal–Wallis (KW...
This means that the one with currently the best phenotype is the first one in this queue (obtains rank 1, i.e., the highest in the population), while the code of the worst phenotype is ordered as the last one (i.e., with K rank, integer number equal to population size). Next, ...
It should be noted that the square terms (i.e., p2 + q2 + r2, etc.) are homozygote frequencies while the others (i.e., 2pq + 2pr + 2qr, etc.) are heterozygotes. Considering several alleles, I, with a frequency, pi, the homozygote frequency is Σpi2 and heterozygote frequency ...