A nonparametric estimate of the mean survival time can be obtained as the area under the Kaplan-Meier estimate of the survival curve. A common modification is to change the largest observation to a death time if it is censored. We conducted a simulation study to assess the behavior of this ...
A nonparametric estimate of the mean survival time can be obtained as the area under the Kaplan-Meier estimate of the survival curve. A common modification is to change the largest observation to a death time if it is censored. We conducted a simulation study to assess the behavior of this ...
Table-4: Kaplan Meier analysis for comparison of mean survival time between two groups. Pattern of relapse in paediatric acute lymphoblastic leukaemia in a tertiary care unit aeruginosa's short survivability, by showing a mean survival time of 5.75 hours. Environmental survivability and surface samplin...
. sts graph, by(group) Kaplan–Meier survival estimates 1.00 0.75 0.50 0.25 group = 1 group = 2 0.00 0 100 200 300 Analysis time 400 The mean survival time reported by rmean is calculated as the area under the Kaplan–Meier survivor function. If the observation with the largest analysis...
Nonparametric Modeling of the Mean Survival Time in a Multi‐factor Design Based on Randomly Right‐Censored Data Nonparametric modeling of the mean survival time in a multi-factor design based on randomly right-censored data. Biometrical Journal. 2004; 46, 497-502... MH Rahbar,JC Gardiner - ...
Restricted mean survival time (RMST) is an alternative measure that may overcome some of the limitations of proportional hazards modeling. RMST is the average time free from an event up until a milestone time point, a numeric expression of the area under the Kaplan-Meier survival curve (1,2...
The difference in restricted mean survival time ( $$ rmstD\left({t}^{\ast}\right) $$ ), the area between two survival curves up to time horizon $$ {t}^{\ast } $$ , is often used in cost-effectiveness analyses to estimate the treatment effect in randomize
In clinical studies, we often consider not only patients' survival time, but also their quality of life. Quality adjusted life years (QALY) is an integrated measure of medical outcome that combines a patient's quantity and quality of life. Estimation of mean QALY for a group of patients is...
The log-rank test is generally a powerful test when there is evident separation favoring 1 treatment arm at most of the time points across the Kaplan-Meier survival curves, but the performance of the RMST test is similar. Under non-PH scenarios where late separation of survival curves is ...
radiotherapy alone in the MAC-NPC and 0.59 years (95% CI: [0.34;0.84], p < 0.0001) in the MAC-NPC2.We recommend the Pooled Kaplan-Meier method with DerSimonian-Laird random effects to estimate the difference in restricted mean survival time from an individual-patient data meta-...