MDS UPDRS-III item-based rigidity and postural stability score estimations: A data-driven approachZhengyu LinRui GuoChencheng ZhangDianyou LiXiaohua QianBomin Sun
DepartmentofNeuroepidemiology,CarlosIIIInstitute,Madrid,Spain 4 DepartmentofNeurology,InnsbruckMedicalUniversity,Innsbruck,Austria 5 DepartmentofPharmacology,FaculdadedeMedicinadeLisboa,Lisboa,Portugal 6 DepartmentofNeurology,UniversityofPennsylvania,Philadelphia,Pennsylvania,USA ...
However, to evaluate the clinical effect during stereotactic neurosurgery or to assess bedridden patients with Parkinson's disease (PD), the MDS-UPDRS-III is often used in a supine position. This explorative study evaluates the agreement of the MDS-UPDRS-III in the sitting and the supine ...
In this study, we examined the sensitivity of five tablet-based tests in predicting changes in the MDS-UPDRS-III scores following controlled Levodopa administration, utilizing regression models trained on data from 28 patients. Our experiments revealed that the best-performing single...
Background The Movement Disorder Society revision of the Unified Parkinson''s Disease Rating Scale (MDS‐UPDRS) was designed to be more sensitive to mild motor severity than the Unified Parkinson''s Disease Rating Scale (UPDRS). Objective To test whether MDS‐UPDRS Part III items provide ...
This supports a MWPWT of 5 points.Conclusions: These findings indicate that a 5-point increase on MDS-UPDRS Part III can be used as a threshold for meaningful worsening of motor signs. This supports the use of time-to-5-point increase on MDS-UPDRS Part III as the primary endpoint for ...
This increase was significant only during the first 15 years of disease for all four parts, including part III scores evaluated in both ON and OFF states. MDS-UPDRS scores for all four parts significantly increase with every HY stage and also with 5-year increments in disease duration in the...
doi:10.1016/j.parkreldis.2015.10.548Dubow, JordanDzyngel, BruceBilbault, ThierryGiovinazzo, AnthonyAgro, AlbertParkinsonism & Related Disorders
Objective: In the context of the COVID-19 pandemic where telemedicine widely substitutes for in-office monitoring of Parkinson's disease (PD), we assessed if the MDS-UPDRS Part III (Motor Examination) taken without ratings that require in-office scoring can provide an accurate surrogate summary ...
Introduction Emerging technologies show promise for enhanced characterization of Parkinson's Disease (PD) motor manifestations. We evaluated quantitative mobility measures from a wearable device compared to the conventional motor assessment, the Movement Disorders Society-Unified PD Rating Scale part III (...