Probes used were DNA fragments of the GFP coding sequence. Mouse IDs are shown at the top of the panel. (B) The mice/D171N + Evi1 were polyclonal. DNA samples were digested with EcoRI. Proviruses were probed wit
Unsupervised clustering analysis as described in the previous section showed that de novo AML also presents with an epigenetic profile distinct from normal bone marrow progenitors (Figure 2A-C). However supervised analysis showed that only 473 fragments (475 genes; supplemental Table 4) were ...