肿瘤防治研究2007年第34卷第5期·351·甲基莲心碱对乳腺癌MCF一7/Adr细胞MDR逆转的研究黄程辉,曹培国TheStudyofNeferineonMultidrugResistanceReversingoftheHumanBreastCancerCellLineM[CF-7/AdrHUANGCheng—hui,CAOPei—guoDepartmentofOncology,TheThirdXiangyaHospitalofCentralSouthUniversity,Changsha410013.ChinaAbstract:Ob...
乙酰化目的:从组蛋白乙酰化修饰角度探讨姜黄素上调乳腺癌MCF-7和MCF-7/DOX细胞中多药耐药基因1(multidrug resistance protein 1,MDR1)表达水平的作用机制.方法:CCK-8(Cell Counting Kit-8)法观察姜黄素对MCF-7和MCF-7/DOX细胞生长增殖以及多柔比星敏感性的影响;Realtime PCR和Western blot方法检测姜黄素处理...
目的 观察乳腺癌相关成纤维细胞(CAFs)对乳腺癌细胞耐药基因表达的影响,探讨微环境对乳腺癌化疗耐药的作用.方法 取10例乳腺癌患者新鲜手术后标本进行原代间质细胞的分离,培养及纯化,并行免疫组化鉴定CAFs.收集CAFs培养上清(CM)与乳腺癌细胞株MCF- 7间接共培养,应用免疫组化法检测与CAFs共培养的乳腺癌细胞株MCF-7及...
5) cell species MCF-7/Taxol 细胞系MCF-7/Taxol6) cell species MCF-7/ADMy 细胞系MCF-7/ADMy补充资料:白细胞细胞系 白细胞细胞系 即经白细胞传代建立的永久性细胞系。这种细胞系仍然保留供者的染色体结构。 说明:补充资料仅用于学习参考,请勿用于其它任何用途。
Silen莽age du g猫ne MDR1 et resensibilisation des cellules MCF-7 MDR 脿 la doxorubicine en utilisant les nanoparticules chitosane/MDR1-siARN 来自 publications.polymtl.ca 喜欢 0 阅读量: 36 作者: ElAriss, Mohamad,Mohamad ElAriss 摘要: Cancer is the leading cause of death in Canada and ...
Doxorubicin-conjugated dexamethasone induced MCF-7 apoptosis without entering the nucleus and able to overcome MDR-1-induced resistance... Kamontip,Chaikomon,Supreecha,... - 《Drug Design Development & Therapy》 被引量: 0发表: 2018年 c-Myc and cyclin D3 (CcnD3) genes are independent targets...
67Ga-metalloprobes (6aand 6b) showed high accumulation in human epidermal carcinoma drug-sensitive KB-3-1 cells (Pgp-), human breast carcinoma MCF-7 (Pgp-) cells; an inhibitor (LY335979, 1 μM) induced accumulation in multidrug resistant (MDR, Pgp+) KB-8-5, KB-8-5-11 cells, and...
Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells. Phytomedicine 20: 622–631. Ueda K, Cardarelli C, Gottesman MM, Pastan I (1987a). Expression of a full-length CDNA for the human "MDR1" gene confers resistance to colchicine, ...
Molecular mechanism of suppression of MDR1 by puerarin from Pueraria lobata via NF-kappaB pathway and cAMP-responsive element transcriptional activity-dependent up-regulation of AMP-activated protein kinase in breast cancer MCF-7/adr cells. Mol Nutr Food Res. 2010;54(7):918-28....
Upregulation of WBP2 in MCF7 cells increased the chemoresistance to doxorubicin, while RNAi-mediated knockdown of WBP2 in MCF7/ADR cells sensitised the cancer cells to doxorubicin. Further investigation in in vitro and in vivo models demonstrated that WBP2 expression was directly correlated with ...