In the present study, using microdialysis, we examined the effects of co-administration of MDMA and PMA with moclobemide on extracellular concentrations of 5-HT and 5-hydroxy indol acetic acid (5-HIAA) in the striatum of the rat. 5-HT-mediated effects on body temperature and behavior were...
Taken in pill form as Ecstasy, the dosage may be anywhere from 10 to 150mg. Some users, however, will up doses to 500 or even 700mg to experience the drug’s effects. This binging behavior is typical at all-night dance parties. Unfortunately, the danger of an MDMA overdose is very ...
Very little research has examined their effect on cognitive function or behavior when combined. The present study used a double Y-maze task to examine the acute effect of MDMA and D9-tetrahydrocannabinol (THC, the principal psychoactive ingredient of cannabis) on mnemonic function in rats, at a...
These findings suggest that MDMA may have specific impact on the retrieval of emotional memory Race representations. The present study sought to disentangle the effects of MDMA on the encoding and retrieval of negative, neutral, and positive memory. Additionally, we sought to distinguish the MDMA ...
Rationale: A variety of animal models have shown MDMA (3,4-methylenedioxymethamphetamine) to be a selective 5-HT neurotoxin, though little is known of the long-term behavioural effects of the pathophysiology. The widespread recreational use of MDMA thus raises concerns over the long-term functional...
MDMA, also known as Molly or Ecstasy, refers to a synthetic amphetamine derivative that lowers inhibitions and alters mood, perception and social behavior.
Candy flipping, the combination of LSD (lysergic acid diethylamide) and MDMA (methylenedioxymethamphetamine), involves the use of two powerful psychoactive substances known for their hallucinogenic and mood-enhancing effects. This practice is popular amo
Neonatal Citalopram Treatment Inhibits the 5-HT Depleting Effects of MDMA Exposure in Rats Neonatal exposure to 3,4-methylenedioxymethamphetamine (MDMA) produces long-term learning and memory deficits and increased anxiety-like behavior. The mech... Tori L. Schaefer,Curtis E. Grace,Matthew R. Skelt...
Meanwhile, alcohol is a depressant that slows the body down. When you mix MDMA and alcohol, they have opposite effects on the body. While some people believe they cancel each other out, they actually lead to a dangerous and potentially fatal combination. As such, it’s never safe to drink...
… manage cookie consent to provide the best experiences, we use technologies like cookies to store and/or access device information. consenting to these technologies will allow us to process data such as browsing behavior or unique ids on this site. not consenting or withdrawing consent, may ...