Metered dose inhalers (MDIs) are a widely used dosage form for pulmonary delivery of anti-asthmatic drugs. However, with the phase-out of chlorofluorocarbon (CFC) propellants and need to switch to the alternative pharmaceutically approved hydrofluoroalkane (HFA) propellants, the MDI formulator was...
Background:Recent investigations revealed that in patients with bronchial asthma the same anti-inflammatory effect is achieved by inhalation of half the dose of budesonide by a Turbuhaler (i.e. by using corticosteroid in powder form) as by a full dose of beclomethasone driven into the lungs by ...