Psychotic Depression(also known asMajor Depressive Disorder with psychotic featuresin the DSM-5) is a subtype ofdepressioncharacterized by psychosis (delusions, hallucinations) in addition to mood changes. It requires the treatment of the underlying mood disorder first to resolve the psychosis. ...
Schizoaffective disorder is different from major depressive disorder with psychotic features because in the schizoaffective disorder at least two weeks of delusions or hallucinations must occur in the absence of prominent mood symptoms. Depressive symptoms may be identified during schizophrenia, delusion...
Effects of antipsychotic medication on functional connectivity in major depressive disorder with psychotic features Article 31 May 2023 Introduction Cognitive behavioral therapy (CBT) is an effective treatment for both major depressive disorder (MDD) and post-traumatic stress disorder (PTSD) with equally...
A similar gradient was observed for hippocampal volume across these disorders35,141,142, suggesting an “affective-psychotic severity continuum” (Fig. 4). Moreover, in ENIGMA, the obsessive–compulsive disorder (OCD) consortium likewise found lower hippocampal volume in OCD patients versus healthy ...
Exclusion criteria were: 1) having a self-reported lifetime history of bipolar disorder, schizophrenia, MDD with psychotic features, or schizoaffective disorder; 2) dementia; 3) having received treatment for drug or alcohol use in the 6 months prior to enrolment; 4) a major medical diagnosi...
Efforts to develop neuroimaging-based biomarkers in major depressive disorder (MDD), at the individual level, have been limited to date. As diagnostic criteria are currently symptom-based, MDD is conceptualized as a disorder rather than a disease with a
The comorbidity of pain and depression is associated with high disease burden for patients in terms of disability, wellbeing, and use of medical care. Patients with major and minor depression often present themselves with pain to a general practitioner a
Consider a gradual approach to quitting smoking with CHANTIX for patients who are sure that they are not able or willing to quit abruptly. Patients should begin CHANTIX dosing and reduce smoking by 50% from baseline within the first four weeks, by an additional 50% in the next four weeks, ...
Patients with major depressive disorder (MDD) and co-morbid chronic pain now have a high risk of not receiving optimal care [1–4]. The burden of co-morbid pain to depression is high for patients in terms of disability, wellbeing, and use of medical care [5]. Complex, integrated collabo...