In addition, our study population was characterized by recurrent moderate MDD; at study onset, about 60% of patients had a prescription for SSRIs, 43% were using SNRIs, and 45% were using NDRIs and tetracyclics. Long duration of MDD together with psychiatric and medical comorbidities are the...
Major depressive disorder (MDD) (also known as recurrent depressive disorder, clinical depression, major depression, unipolar depression, or unipolar disorder) is a mental disorder characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in no...
The Recurrent Neural Network (RNN) shows an improvement, with an accuracy of 85.45%, precision of 84.43%, and recall of 85.03%. This enhancement reflects the RNN’s ability to better handle sequential data, capturing temporal dependencies more effectively than the CNN. The Bidirectional Long ...
MDD patients taking antidepressants at the time of scanning were likely the most severe/chronic or recurrent patients in the sample, so the results are likely to be confounded by the severity or course of the disorder. Potential neuroprotective effects of antidepressant medication are more consistent...
DSM criteria are currently less useful for measuring psy- chiatric symptoms and disorders on a continuum. Major depressive disorder is classified as a mood disorder, with diagnosis hinging on the presence of a single episode or of recurrent major depressive episodes (MDE) [1]. The gold ...
May be used as first-line in mild-moderate depression When is Vagal Nerve Stimulation (VNS) used? what are side effects? ADJUNCTIVE treatment for CHRONIC, recurrent depression (lasting 2 years, not responding to >4 trials of ADs) in patients >18 years old ...
University of California at San Francisco (UCSF) cohort consists of first episode and recurrent MDD and healthy control participants [70, 71]. Assessments MDD diagnosis is based on standardised diagnostic criteria, DSM or ICD: DSM-IV (HMRRC, Manchester, Oxford, PReDICT, SWU), DSM-IV-TR (CAN...
Exclusion Criteria: (1) Patients diagnosed with schizoaffective disorder, dysthymia, or bipolar depression; those primarily diagnosed with any other anxiety disorder within the last year; individuals with substance dependence; or those with personality disorders. (2) Carriers/patients of hepatitis B or...