This is similar to the results observed in another real-world study, which reported significant improvement in the severity of anxiety symptoms, from “severe” anxiety at baseline to “mild” over 52 weeks of vortioxetine treatment [8]. Furthermore, in another recent open-label study in adult...
The comorbidity of pain and depression is associated with high disease burden for patients in terms of disability, wellbeing, and use of medical care. Patients with major and minor depression often present themselves with pain to a general practitioner a
]. Among patients with residual symptoms, > 90% had mild-to-moderate physical symptoms including pain [32]. Improvement in painful physical symptoms is associated with higher remission rates in MDD [35]. In a study in newly referred neurologic outpatients, pain occurred in 10-55% of several ...