首先,在正常的MDCK细胞中转染人MRP2 cDNA,构建MRP2过表达的MDCK/MRP2细胞。检测MDCK以及MDCK/MRP2细胞对35种黄酮类化合物(橘皮素、白杨素、木樨草素、牡荆素、异牡荆素、山柰酚、芦丁、槲皮素、漆黄素、柚皮苷、水飞蓟素、黄豆黄素、异...
MDCKII MRP2 cellsNon-ionic surfactantsEfflux transportersThe aim of the present study was to investigate the ability of non-ionic surfactants to inhibit MRP2-mediated transport in vitro in MDCKII MRP2 cells. Transport studies across MDCKII MRP2 cell monolayers were performed using H-3-etoposide and...
Multidrug resistance-associated protein 2 is involved in the efflux of Aconitum alkaloids determined by MRP2-MDCKII cells[J].Life sciences 2015.Dai PM,Zhu LJ,Yang XS,et al.Multidrug resistanceassociated protein 2 is involved in the efflux of Aconitum alkaloids determined by MRP2-MDCKII cells[J]...
Chelerythrine increases glutathione export by the rat multidrug resistant protein MRP2 in madin-darby canine kidney (MDCK) II cellsHelicobacter heilmanniiacute gastric mocosal lesionstouch cytologyA 69-year-old-woman presented with acute epigastric pain, nausea, vomiting and heartburn. Endoscopy ...
Fernandez SB, Hollo Z, Kern A, Bakos E, Fischer PA, Borst P, Evers R (2002) Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells. J Biol Chem 277:31048-31055...
Construction and Characterization of Double-Transfected MDCKII cells Stably Expressing Human OAT1 and MRP2Kan Chen
Functional Characterization of a Hepatic Organic Anion Transport Model; OATP1B1 and MRP2 Double Transfected MDCKII cellsKelly Bleasby
Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathwayEfflux transportersFlavonoidsGlucuronide"Revolving door"UGTScope: The purpose of this study is to characterize how overexpression of an efflux transporter and ...
Transcellular transport of organic anions across MDCK II monolayers expressing human OATP2 and Mrp2: Makoto Sasaki, Hiroshi Suzuki, Yuichi Sugiyama, University of Tokyo, Tokyo Japandoi:10.1053/S0270-9139(00)83344-3ELSEVIERHepatology