Miller LD, Smeds J, George J, Vega VB, Vergara L, Ploner A, Pawitan Y, Hall P, Klaar S, Liu ET, Bergh J: An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci USA. 2005, 102: 13550...
The arrest during the G1 phase of cell division, irrespective of ER, HER2, and p53 status, triggers apoptosis by inhibiting telomeres44. This inhibition also effectively prevented cancer from spreading to other body parts (metastasis). Furthermore, multiple studies have recognized that the arrest ...
EVs, or EGCG-EVs (Fig.3A). Densitometry analysis perfomed on duplicate lysates from two independent membranes demonstrated that P38a, STAT5a/b and P53 phosphorylation status were induced, but unmodified upon any treatment
Experiment Cell Res 289: 265 – 274 Wang JL, Sun Y, Wu S (2000) Gamma-irradiation induces matrix metalloproteinase II expression in a p53-dependent manner. Mol Carcinog 27: 252 – 258 White KE, Ding Q, Moore BB, Peters-Golden M, Ware LB, Matthay MA, Olman MA (2008) Prostaglandin ...
Nuclear translocation of annexin 1 following oxygen-glucose deprivation-reperfusion induces apoptosis by regulating Bid expression via p53 binding Cell Death Dis., 7 (9) (2016), Article e2356 CrossrefView in ScopusGoogle Scholar [16] M. Sakaguchi, H. Murata, H. Sonegawa, Y. Sakaguchi, J. ...
Parssinen J, Alarmo EL, Karhu R, Kallioniemi A: PPM1D silencing by RNA interference inhibits proliferation and induces apoptosis in breast cancer cell lines with wild-type p53. Cancer Genet Cytogenet. 2008, 182: 33-39. 10.1016/j.cancergencyto.2007.12.013. Article PubMed Google Scholar Pars...
density [28,29] but is not related to p53 status or VEGF expres- sion [30]. Endogenous TSP1 inhibits primary tumor growth and angiogenesis but promotes metastasis to the lung in the Pyt transgenic mouse breast cancer model [31]. TSP1 stimulates breast carcinoma cell adhesion and chemotaxis ...
Miller LD, Smeds J, George J, Vega VB, Vergara L, Ploner A, Pawitan Y, Hall P, Klaar S, Liu ET, Bergh J: An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci USA. 2005, 102: 13550...
In breast cancer, KHSRP was destabilized by the mutant p53–proteasome axis, indicating the functional realization of KHSRP was under p53 mutation pathway39. Meanwhile, recent studies also demonstrated the pro-oncogenic function of KHSRP in multiple cancers (see introduction). Based on our results,...
(1 : 500), anti-Akt1/2 (1 μg ml−1), anti-phosphoAkt1/2 (1 : 1000), anti-ERK1/2 (1 : 200), anti-phosphoERK1/2 (1 : 200), anti-c-Src (1 μg ml−1), anti-phospho-c-Src (2 μg ml−1), anti-p53 (1 : 1000) or anti-...