(a) Cell cycle status for untreated MDA-MB-231 cells and cells treated by nrCap18. (b) The percentage of cell population in different cell cycle phases. *P < 0.05, **P < 0.01, ****P < 0.0001. Full size image Wound-healing assay for cell migration Results showed that ...
The family of long noncoding mitochondrial RNAs (ncmtRNAs), comprising sense (SncmtRNA), and antisense (ASncmtRNA-1 and ASncmtRNA-2) members, are differentially expressed according to cell proliferative status; SncmtRNA is expressed in all proliferating
(B) Dot plot showing the correlation analysis result between KHSRP and the selected DEGs using BRCA dataset from TCGA. Full size image KHSRP regulates alternative splicing genes enriched in DNA repair in MDA-MB-231 cells As an RBP, KHSRP has the ability to regulate alternative splicing pattern ...
This result is in concordance with the increase in expression levels of HA, HAS2 and BRCA1 and with previously published data. Although it will be necessary to expand the cohort of studied patients to confirm the results, this analysis complements our in vitro assays, and proposes a starting ...