TNBC cell line has no expression of estrogen receptor (ER), progesterone receptor (PR), and enriched human epidermal growth factor receptor 2 (HER2). MDA-MB-468 highly expressed glucose-6-phosphate dehydrogenase (G6PD). MDA-MB-468 presents basal-like tumors of TNBC and epithelial-like ...
Overexpression of m-hTRβ1 inhibits the proliferation of MDA-MB-468 cells in the presence of triiodothyronine by promoting apoptosis, which may be associated with the upregulation of Caspase-3 and Bak gene expression and the activation of the Caspase-3 protein. In addition, the pro-apoptotic ...
Formononetin and everolimus also inhibited the expression of p-mTOR and p-P70S6K and increased the expression of PTEN and p-4EBP-1. Notably, formononetin alone inhibited p-Akt expression but not everolimus.Formononetin enhances the tumoricidal effect of everolimus by inhibiting the activity ...
Furthermore, these genes do not show expression differences in Triple-negative Basal cells (MDA468) when compared to MCF10A cells and HER2+ cells (SKBR3) present residual (HOXB8) or null expression (HOXB9). Download: Download high-res image (455KB) Download: Download full-size image Fig....
Accordingly, the aim of this study was to investigate the effects of Chinese medicinal herbs on the BDNF-related interaction between MDA-MB-231 and HUVEC cells. Methods Cell line and reagents The human triple negative breast cancer cell line MDA-MB-231 (ER-low, PR-low and HER2-low) was ...
Accordingly, the aim of this study was to investigate the effects of Chinese medicinal herbs on the BDNF-related interaction between MDA-MB-231 and HUVEC cells. Methods Cell line and reagents The human triple negative breast cancer cell line MDA-MB-231 (ER-low, PR-low and HER2-low) was ...
EGF-related peptides are involved in the proliferation and survival of MDA-MB-468 human breast carcinoma cells A majority of human breast carcinomas co-express the epidermal growth factor (EGF)-like peptides CRIPTO (CR), amphiregulin (AR) and transforming growth fac... AD Luca,A Casamassimi...
International Journal of Molecular Sciences Article Metformin Inhibits Migration and Invasion by Suppressing ROS Production and COX2 Expression in MDA-MB-231 Breast Cancer Cells Chandler Schexnayder 1, Kiera Broussard 1, Demitrius Onuaguluchi 1, Anthony Poché 1, Moamen Ismail 2, LeFontae McAtee ...
Figure S1 A MDA-MB-2317-ALDHA1/tdTomato 2 tdTomato- cells (nonCSC) 1.5 tdTomato+ cells (CSC) B MDA-MB-231 1 0.5 0 CD44 CD24 Invasion CD24 Figure S1. CD44 and CD24 expression in MDA-MB-2317-ALDHA1/tdTomato cells. qPCR quantification of CD44 and CD24 did not revealed any ...
MCF-7 (ER, PR, HER2 positive) and TNBC cell lines MDA-MB-231 and MDA-MB-468 were treated with triptolide at concentrations of 100 pM, 1 nM, 10 nM, 100 nM, 1 µM, and 10 µM for 72 h. After treatment, the cell lines showed distinct differences in sensitivity to triptolide ...