PROBLEM TO BE SOLVED: To obtain an MCP-1 receptor antagonist useful for inflammatory disease or organopathy relating to MCP-1 by including an organic germanium compound as an active component.ISHIWATARI YOSHIRO石渡 義郎YOKOCHI SHOJI横地 祥司...
development of atherosclerotic lesions. MCP-1 plays a crucial role in initiating atherosclerosis by recruiting macrophages and monocytes to the vessel wall. Development of therapeutic drugs for atherosclerosis specifically targeted against MCP-1 and/or its receptor, CCR-2, may prove useful in the preve...
近年来研究发现MCP-1及其基因多态性与2型糖尿病及其慢性并发症密切相关,但是与DPN的相关研究较少。有研究表明,MCP-1通过其受体(CC chemokine receptor 2,CCR2)在促进慢性神经性疼痛中发挥重要作用[12、13]。 而CCR2基因敲除小鼠在神经损伤模型...
Anti-Eph receptor B2/Ephb2 Ephb2抗体 Multi-class antibodies 规格: 0.1mlAnti-ERK1/MAPK3 丝裂原活化蛋白激酶3抗体 Multi-class antibodies 规格: 0.1ml更多的单核细胞趋化蛋白1(MCP-1)检测试剂盒说明书,单核细胞趋化蛋白1(MCP-1)检测试剂盒报价,单核细胞趋化蛋白1(MCP-1)检测试剂盒*,请我们!
CCR2 is the major MCP-1 receptor, and MCP-1 binds to CCR2 with high affinity.6, 7, 8 In addition to chemotaxis, chemokines can influence differentiation of lymphocytes into Th1 or Th2 cells, with MCP-1 promoting Th1 cell development. Because our model of EHP appears to be mediated by...
(sTREM-2)ELISA试剂盒Human soluble myeloid cell trigger receptor-2 (sTREM-2) ELISA kit 人受体相互作用蛋白(RIP)ELISA试剂盒Human Receptor Interacting Protein (RIP) ELISA Kit 人卵磷脂胆固醇酰基转移酶(LCAT)ELISA试剂盒Human Lecithin Cholesterol Acyltransferase (LCAT) ELISA Kit 人结蛋白(Desmin)ELISA试剂...
The invention relates to antibodies which is capable of binding the monocyte chemoattractant protein 1 (MCP-1) receptor CCR2, especially those which are capable of acting either as an antagonist or agonist. The claimed antobodies can be used for in vitro and/or in vivo diagnostic, for screenin...
Irbesartan, an angiotensin II type 1 receptor blocker, inhibits colitis-associated tumourigenesis by blocking the MCP-1/CCR2 pathway[J].Sci Rep, 2021,11(1):19943.[7] Chen S, Zhang YY, Zhang H, et al. Anti-inflammatory effects of NaB and NaPc in Acinetobacter baumannii-stimulated THP-1...
Monocyte chemoattractant protein-1 (MCP-1) and its receptor CCR-2 are known to play a major role in inflammatory responses after cerebral ischemia. Mice deficient in either MCP-1 or CCR-2 have been reported to develop smaller infarct sizes and show decreased numbers of infiltrating inflammatory ...
The receptors, which are alternately spliced versions of MCP-1 receptor protein may be used in an assay to identify antagonists of MCP-1 which are therapeutically useful in the treatment of atherosclerosis and other diseases characterized by monocytic infiltrates.Israel Charo...