Tye. 1993. Cell cycle-regu- lated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast. Genes & Dev. 7: 2149-2160.Yan, H., Merchant, A.M., and Tye, B.K. (1993). Cell cycle-regulated nuclear ...
采用cell counting kit-8 (CCK-8)、平板细胞克隆形成、Transwell 和Invasion 实验证实，MCM2可促进胆管癌细 胞的增殖、迁移和侵袭能力；流式细胞术检测结果显示，MCM2可加快细胞周期进程，抑制细胞凋亡。进一步 通过对胆管癌组织RNA 测序数据集的分析发现，MCM2基因与p53信号通路的激活显著负相关。采用实时定 量PCR ...
MCM2, also named CDCL1 and BM28, is a human nuclear protein that plays an important role in 2 crucial steps of the cell cycle, namely, onset of DNA replication and cell division. 实验方案 Product Specific Protocols WB protocol for MCM2 antibody 84511-5-RR Download protocol IHC protocol ...
MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its ...
revealed that sine oculis homeobox homolog 1 (SIX1) enhanced the MCM2 level to further accelerate the initiation of DNA replication and cell cycle in cervical cancer (Liu et al. 2014). In summary, MCM2 has the potential to promote cancer progression. Nevertheless, more efforts are needed to...
MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its ...
MCM2, also named CDCL1 and BM28, is a human nuclear protein that plays an important role in 2 crucial steps of the cell cycle, namely, onset of DNA replication and cell division. Properties Storage Instructions All the reagents are stored at 2-8°C. The kit is stable for 6 months ...
MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S phase proteins. Mincheva et al. (1994) mapped the gene to...
微小染色体维持缺陷蛋白2(MCM2)重组蛋白 别名: BM28; CCNL 1; CCNL1; CDC like 1; cdc19; CDCL 1; CDCL1; Cell devision cycle like 1; Cyclin like 1; D3S3194; DNA replication licensing factor MCM2; KIAA0030;
This complex is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. MCM2, also named CDCL1 and BM28, is a human nuclear protein that plays an important role in 2 crucial steps of the cell cycle, namely, onset ...