Paraffin-embedded tumor tissues from patients and nude mice were sectioned to generate 5 μm sections, which were deparaffinized and rehydrated. After blocking endogenous avidin and biotin, antigen retrieval was performed using sodium citrate buffer at high temperature for 20 min. The antigens were...
(HDACi); MICA; natural killer cells; microRNA; MCM7 Histone deacetylase inhibitor SAHA epigenetically regulates miR-17-92 cluster and MCM7 to upregulate MICA expression in hepatoma H Yang1, P Lan1, Z Hou1, Y Guan1, J Zhang1,2, W Xu3, Z Tian4 and C Zhang*,1,2 1Institute of ...
3 evento más Organizador ¿Consultas sobre el evento?Preguntar al organizador Asociación Internacional de Academias, Investigación e Industria (IARIA)EE. UU.587Total de eventos•231Seguidores Mapa del lugar y direcciones Hoteles NovHotel Nice Aeroport Cap 3000 ...
La increíble apariencia y calidad de los productos de arcilla modificada que sustituyen y reemplazan las piedras tradicionales, los azulejos, los ladrillos, el papel tapiz, el cuero, el metal y los pisos de madera en cualquier forma o perfil...
26. Zhou H, Xiong Y, Zhang G, Liu Z, Li L, Hou S, et al. Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer. Biosci Rep. 2020;40(7). https://doi.org/10.1042/...
The controlled assembly of replication forks is critical for genome stability. The Dbf4-dependent Cdc7 kinase (DDK) initiates replisome assembly by phosphorylating the MCM2-7 replicative helicase at the N-terminal tails of Mcm2, Mcm4 and Mcm6. At present
The oligonucleotides 5′-GGCGTGTGCTGCATTGCTGCGTTTGACAAGATGGCC-3′ and 5′-GACCCTGGTGTGGCCGCAGCTCAGCTCCTATCTTAC-3′ were used as primers to prepare the histidine-tagged Mcm7DE and Mcm7KS mutants (where “DE” refers to the Asp444 and Glu445 residues in the Walker B motif mutated to ...
EMBO Rep 7: 539–545. [12] Yoshimochi T, Fujikane R, Kawanami M, Matsunaga F, Ishino Y (2008) The GINS complex from Pyrococcus furiosus stimulates the MCM helicase activity. J Biol Chem 283: 1601–1609. [13] De Falco M, Ferrari E, De Felice M, Rossi M, Hubscher U, et al. (...
Employing the DeSeq2 R package, we then identified genes with joint differential expression in GBM tissues subjected to chemotherapy. To develop a prognostic risk score model, we performed univariate and multivariate Cox regression analyses. In vitro knockdown and overexpression of MCM5 were used to...
MCM305 快速启动指南说明书 Guía de inicio rápido Paso A Paso B Paso C Conexión Configuración Disfrutar Contenido de la caja Verifique el contenido de la caja e identifique las siguientes piezas:Control remoto Guía de inicio rápido Manual de usuario Cable de conexión MP3Adaptador de pin ...