MCF2L -AS1可能与细胞周期等生物学功能密切相关。结论 lncRNA MCF2L -AS1在胃癌细胞与组织中高表达，并促进胃癌细胞的增殖、侵袭和迁移。关键词 长链非编码RNA； MCF2L -AS1； 胃癌； 增殖； 侵袭； 迁移 中图分类号 R735.2 文献标志码 A ...
O R I G I N A L R E S E A R C HlncRNA MCF2L-AS1/miR-105/ IL-1β Axis Regulates Colorectal Cancer Cell Oxaliplatin ResistanceMao Cai* Wanle Hu* Chongjie Huang Chongjun Zhou Jiante Li Yanyu Chen Yaojun YuDepartment of Anorectal Surgery, The Second Aff i liated Hospital of Wenzho...
Objective: To investigate the effect of lncRNA MCF2L-AS1 on the malignant biological behavior of gastric cancer cells and its molecular mechanism. Methods: The expression levels of MCF2L-AS1 and miR-33b-5p in cancer tissues and paracancerous tissues of 45...
colorectal cancerlncRNA MCF2L‐AS1miR‐874‐3pLong non‐coding RNAs (lncRNAs) have drawn growing attention because of the role which they play in various diseases, including colorectal cancer (CRC). However, the potential functions of lncRNA MCF2L antisense RNA 1 (MCF2L‐AS1) in tumors ...
miR-33b-5p胃癌增殖迁移侵袭凋亡目的:探讨lncRNA MCF2L-AS1对胃癌细胞恶性生物学行为的影响及分子机制.方法:选取45例胃癌患者的癌组织及癌旁正常组织,或培养胃黏膜上皮细胞GES-1,胃癌细胞HGC-27,采用RT-qPCR检测MCF2L-AS1和miR-33b-5p的表达水平.采用双荧光素酶报告实验检测MCF2L-AS1和miR-33b-5p的靶向关系....
We found high lncRNA MCF2L-AS1 expression in human bone marrow mesenchymal stem cells, and used bioinformatics analysis to analyze its function. MCF2L-AS1 knockdown induced inhibition of osteoblast differentiation. Silencing of MCF2L-AS1 increased the expression of miR-33a and subsequently inhibited ...
lncRNA MCF2L‐AS1miR‐874‐3pLong noncoding RNAs (lncRNAs) have drawn growing attention because of the role which they play in various diseases, including colorectal cancer (CRC). However, the potential functions of lncRNA MCF2L antisense RNA 1 (MCF2L〢S1) in tumors remained largely unclear....
MCF2L‐AS1miR‐873‐5pThe roles of long noncoding RNA (lncRNA) MCF2L〢S1 have been identified in colorectal cancer, however, its roles in lung cancer progression have never been revealed. Here, we found that lncRNA MCF2L〢S1 was highly expressed in lung cancer tissues and cells, ...