BIOLOGICALACTIVITY⽣物活性Tauro-β-muricholicAcidsodium(T-βMCAsodium)⼀种内性代谢物,⼀种竞争性、可逆的FXR拮抗剂,其IC50值为40μM[1][2][3]。IC50&TargetIC50:40μM(FXR)[1]体外研究T-βMCAsodiuminhibitsFXRreporteractivityintheCRCcelllineHT29(EC50~10μM)[3].T-βMCAsodiumdose-dependently...