The genO‑MC38-hPD-L1-hCD47-LZ clonal cell line expresses high levels of human PD-L1 and human CD47. genO-hCT26-hPD‑L1 The humanized hPD-L1 syngeneic clonal colon carcinoma CT26 cell line expresses high levels of human PD-L1 and forms solid tumorsin vivo. ...
细胞系名称 MC38 目录号 NM-S13 品系描述 小鼠结肠癌细胞系 品系状态 成瘤性验证完成 *使用本品系发表的文献需注明: MC38 cell line (Cat. NO. NM-S13) was purchased from Shanghai Model Organisms Center, Inc.. 验证数据 Figure 1. Tumor growth curve of MC38 allogeneic model (n=5) ...
Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res. 35:2434-2439(1975) MC38小鼠结肠癌细胞接受后处理 1) 收到细胞后,请检查是否漏液 ,如果漏液,请拍照片发给我们。 2) 请先在显微镜下确...
细胞系名称 MC38-OVA-Luc (2) 目录号 NM-S13-TG69 品系描述 The MC38-OVA-Luc cell line is the MC38 colon cancer tumor cell line expressing OVA gene and protein. 品系状态 成瘤性验证完成 *使用本品系发表的文献需注明: MC38-OVA-Luc (2) cell line (Cat. NO. NM-S13-TG69) was purchase...
Here we continue characterization of a C57BL/6 transgenic mouse model expressing both the human PD-1 and PD-L1 combined with a modified murine MC38 colon tumor cell line expressing human PD-L1. Both PD-1 and PD-L1 expression of the transgenic mice were verified in ex vivo stimulated sple...
et al. "The immune landscape of cancer." Immunity 48.4 (2018): 812-830.[7] Peters, Solange. "Tumor mutational burden (TMB) as a biomarker of survival in metastatic non-small cell lung cancer (mNSCLC): Blood and tissue TMB analysis from MYSTIC, a Phase III study of first-line durvalu...
OVA expression in wild-type MC38 and MC38-OVA-Luc cell lines Shanghai Model Organisms Center, Inc. www.modelorg.com 1/3 Figure 2. Tumor growth curve of MC38 and MC38-OVA-Luc syngeneic model (n=4) Figure 3. Body weight curve of MC38 and MC38-OVA-Luc syngeneic model (n=4) ...
Expression analysis by FACS. mPd-l1 expression in genO-MC38‑Pd‑l1KO clone and parental cell line. genO-MC38-Pd-l1KO cells form tumorsin vivo Wild-type Balb/c mice were injected (s.c.) with 1x105MC38.WT (A) or genO-MC38-Pd-l1KO (B) cells. Tumor growth was measured every...
Tumor volumes in anti-PD-L1 and anti-PD-1 treated mice were also smaller than those in isotype controls starting day 22 post-tumor inoculation (509+103 and 504+94mm3 vs 899+124mm3, respectively, on day 22). Because radiotherapy is thought to increase the immunogenicity of tumors, we ...
Anti-tumor immunotherapyGenetic vaccineCEACAM64-1BBLAnti-PD1 drugWe used mouse CRC cell line (MC38) to establish a heterotopic mouse model, and applied [89Zr]-labeled PD-L1 antibody for PET imaging. Attenuated Sdoi:10.2139/ssrn.4064543Li, Yuzhen...